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Atomistry » Chlorine » PDB 8ayq-8b7b » 8b75 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8ayq-8b7b » 8b75 » |
Chlorine in PDB 8b75: Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with the Inhibitor Tdi-011861Enzymatic activity of Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with the Inhibitor Tdi-011861
All present enzymatic activity of Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with the Inhibitor Tdi-011861:
4.6.1.1; Protein crystallography data
The structure of Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with the Inhibitor Tdi-011861, PDB code: 8b75
was solved by
C.Steegborn,
M.Kehr,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8b75:
The structure of Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with the Inhibitor Tdi-011861 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with the Inhibitor Tdi-011861
(pdb code 8b75). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with the Inhibitor Tdi-011861, PDB code: 8b75: Chlorine binding site 1 out of 1 in 8b75Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human Soluble Adenylyl Cyclase in Complex with the Inhibitor Tdi-011861
![]() Mono view ![]() Stereo pair view
Reference:
M.Miller,
T.Rossetti,
J.Ferreira,
L.Ghanem,
M.Balbach,
N.Kaur,
L.R.Levin,
J.Buck,
M.Kehr,
S.Coquille,
J.Van Den Heuvel,
C.Steegborn,
M.Fushimi,
E.Finkin-Groner,
R.W.Myers,
S.Kargman,
N.J.Liverton,
D.J.Huggins,
P.T.Meinke.
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (Sac, ADCY10) Inhibitors with Slow Dissociation Rates. J.Med.Chem. V. 65 15208 2022.
Page generated: Sun Jul 13 09:26:32 2025
ISSN: ISSN 0022-2623 PubMed: 36346696 DOI: 10.1021/ACS.JMEDCHEM.2C01133 |
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