Chlorine in PDB 8bb1: T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase

All present enzymatic activity of T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase:
2.5.1.4; 2.5.1.6;

The binding sites of Chlorine atom in the T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase (pdb code 8bb1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase, PDB code: 8bb1:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl201 b:126.6 occ:1.00 NZ E:LYS78 4.2 134.9 1.0 CE E:LYS101 4.2 101.6 1.0 O E:VAL99 4.2 117.8 1.0 N E:GLY108 4.4 126.5 1.0 CA E:GLY108 4.5 128.7 1.0 O E:THR106 4.6 104.0 1.0 CE2 E:PHE11 4.9 110.3 1.0 C E:ALA107 4.9 113.4 1.0 CG1 E:VAL99 5.0 105.8 1.0

Chlorine binding site 2 out of 4 in the T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl201 b:126.8 occ:1.00 NZ F:LYS78 4.2 134.0 1.0 CE F:LYS101 4.2 101.2 1.0 O F:VAL99 4.2 118.8 1.0 N F:GLY108 4.4 126.9 1.0 CA F:GLY108 4.5 129.3 1.0 O F:THR106 4.6 104.1 1.0 C F:ALA107 4.9 112.8 1.0 CE2 F:PHE11 4.9 111.2 1.0 CG1 F:VAL99 5.0 106.9 1.0

Chlorine binding site 3 out of 4 in the T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase within 5.0Å range: probe atom residue distance (Å) B Occ G:Cl201 b:127.5 occ:1.00 NZ G:LYS78 4.2 133.8 1.0 CE G:LYS101 4.2 101.3 1.0 O G:VAL99 4.2 117.3 1.0 N G:GLY108 4.4 125.8 1.0 CA G:GLY108 4.5 128.2 1.0 O G:THR106 4.6 105.0 1.0 CE2 G:PHE11 4.9 109.5 1.0 C G:ALA107 4.9 112.6 1.0 CG1 G:VAL99 5.0 105.9 1.0

Chlorine binding site 4 out of 4 in the T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of T3 Sam Lyase in Complex with S-Adenosylmethionine Synthase within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl201 b:129.8 occ:1.00 NZ H:LYS78 4.2 134.3 1.0 CE H:LYS101 4.2 102.0 1.0 O H:VAL99 4.2 117.5 1.0 N H:GLY108 4.4 124.8 1.0 CA H:GLY108 4.5 127.2 1.0 O H:THR106 4.6 104.4 1.0 C H:ALA107 4.9 112.2 1.0 CE2 H:PHE11 4.9 110.5 1.0 CG1 H:VAL99 5.0 105.3 1.0

A.Andriianov, S.Triguis, A.Drobiazko, N.Sierro, N.V.Ivanov, M.Selmer, K.Severinov, A.Isaev. Phage T3 Overcomes the Brex Defense Through Sam Cleavage and Inhibition of Sam Synthesis By Sam Lyase. Cell Rep V. 42 12972 2023.
ISSN: ESSN 2211-1247
PubMed: 37578860
DOI: 10.1016/J.CELREP.2023.112972