Chlorine in PDB 8f7l: Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S

Enzymatic activity of Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S

All present enzymatic activity of Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S:
2.4.2.12;

Protein crystallography data

The structure of Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S, PDB code: 8f7l was solved by K.Ratia, R.Xiong, Z.Shen, G.R.Thatcher, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	65.58 / 2.20
*Space group*	P 1 2₁ 1
*Cell size a, b, c (Å), α, β, γ (°)*	60.888, 106.997, 83.603, 90, 96.88, 90
*R / R_free (%)*	22.6 / 26.4

Other elements in 8f7l:

The structure of Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S also contains other interesting chemical elements:

Fluorine

(F)

2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S (pdb code 8f7l). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S, PDB code: 8f7l:

Chlorine binding site 1 out of 1 in 8f7l

Go back to

Chlorine Binding Sites List in 8f7l

Chlorine binding site 1 out of 1 in the Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S

Mono view

Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Cl1004 b:60.5 occ:1.00	N	A:LYS77	3.3	41.1	1.0
	CA	A:THR76	3.6	36.8	1.0
	CB	A:THR76	3.7	35.9	1.0
	CD1	A:LEU105	3.8	32.2	1.0
	C	A:THR76	3.9	41.3	1.0
	CD2	A:LEU105	4.0	40.6	1.0
	NZ	A:LYS73	4.1	45.2	1.0
	CE	A:LYS73	4.1	39.7	1.0
	CB	A:LYS77	4.2	46.6	1.0
	CG2	A:THR76	4.2	35.4	1.0
	CA	A:LYS77	4.3	43.5	1.0
	CG	A:LEU105	4.5	37.4	1.0
	OE1	A:GLU78	4.5	53.7	1.0
	O	A:VAL75	4.7	34.2	1.0
	N	A:THR76	4.9	34.5	1.0

Reference:

K.Ratia, R.Xiong, Z.Shen, G.R.Thatcher. Human Nampt in Complex with Substrate Nam and Small Molecule Activator Zn-29-S To Be Published.

Page generated: Sun Jul 13 11:18:08 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy