Chlorine in PDB 8fr0: Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)

The binding sites of Chlorine atom in the Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) (pdb code 8fr0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260), PDB code: 8fr0:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1302 b:64.7 occ:1.00 CL A:CYZ1302 0.0 64.7 1.0 C13 A:CYZ1302 1.8 32.4 1.0 C12 A:CYZ1302 2.8 27.5 1.0 C14 A:CYZ1302 2.8 25.6 1.0 O4 A:CYZ1302 3.0 44.8 1.0 S2 A:CYZ1302 3.2 41.3 1.0 N A:ASP760 3.3 29.7 1.0 CB A:LEU759 3.5 26.5 1.0 N3 A:CYZ1302 3.5 33.9 1.0 OD1 A:ASP760 3.5 50.9 1.0 CG A:ASP760 3.5 48.6 1.0 C A:LEU759 3.7 29.2 1.0 CA A:ASP760 3.7 32.5 1.0 OD2 A:ASP760 3.9 42.6 1.0 CB A:ASP760 3.9 37.0 1.0 O A:HOH1401 4.0 10.0 1.0 C11 A:CYZ1302 4.0 24.8 1.0 C10 A:CYZ1302 4.1 25.7 1.0 CA A:LEU759 4.2 24.5 1.0 O A:LEU759 4.2 33.7 1.0 O A:PHE495 4.5 27.6 1.0 C9 A:CYZ1302 4.6 24.6 1.0 CG A:LEU759 4.6 28.1 1.0 CD1 A:LEU759 4.6 22.1 1.0 CB D:SER729 4.7 33.1 1.0 O3 A:CYZ1302 4.8 30.3 1.0 N A:LEU759 4.9 31.2 1.0

Chlorine binding site 2 out of 4 in the Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1302 b:73.5 occ:1.00 CL B:CYZ1302 0.0 73.5 1.0 C13 B:CYZ1302 1.8 47.5 1.0 C12 B:CYZ1302 2.7 45.4 1.0 C14 B:CYZ1302 2.8 42.4 1.0 OD1 B:ASP760 3.0 62.6 1.0 O4 B:CYZ1302 3.0 51.1 1.0 S2 B:CYZ1302 3.2 60.7 1.0 CB B:LEU759 3.4 42.9 1.0 O B:HOH1401 3.4 42.3 1.0 N3 B:CYZ1302 3.5 44.3 1.0 N B:ASP760 3.6 51.5 1.0 C B:LEU759 3.6 45.4 1.0 O B:LEU759 3.9 49.4 1.0 CA B:ASP760 4.0 51.4 1.0 C11 B:CYZ1302 4.0 46.7 1.0 CG B:ASP760 4.1 59.8 1.0 C10 B:CYZ1302 4.1 40.7 1.0 CA B:LEU759 4.2 43.1 1.0 O B:PHE495 4.3 38.5 1.0 CD1 B:LEU759 4.5 40.2 1.0 C9 B:CYZ1302 4.6 42.4 1.0 CG B:LEU759 4.6 43.0 1.0 CB B:ASP760 4.7 55.9 1.0 O3 B:CYZ1302 4.8 50.6 1.0 OG C:SER729 4.9 53.0 1.0

Chlorine binding site 3 out of 4 in the Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1302 b:63.3 occ:1.00 CL C:CYZ1302 0.0 63.3 1.0 C13 C:CYZ1302 1.8 30.0 1.0 C12 C:CYZ1302 2.8 27.5 1.0 C14 C:CYZ1302 2.8 24.6 1.0 O4 C:CYZ1302 3.0 44.0 1.0 N C:ASP760 3.2 29.1 1.0 S2 C:CYZ1302 3.2 41.0 1.0 CB C:LEU759 3.5 23.8 1.0 N3 C:CYZ1302 3.5 34.7 1.0 CA C:ASP760 3.6 33.1 1.0 C C:LEU759 3.6 28.8 1.0 CB C:ASP760 3.8 37.6 1.0 OD1 C:ASP760 3.8 48.5 1.0 O C:HOH1401 4.0 11.1 1.0 C11 C:CYZ1302 4.0 26.5 1.0 C10 C:CYZ1302 4.1 23.4 1.0 CA C:LEU759 4.1 21.5 1.0 O C:LEU759 4.2 35.1 1.0 CG C:ASP760 4.2 48.0 1.0 C9 C:CYZ1302 4.6 28.5 1.0 O C:PHE495 4.6 28.4 1.0 CG C:LEU759 4.7 32.0 1.0 CD1 C:LEU759 4.7 22.8 1.0 O3 C:CYZ1302 4.8 32.1 1.0 N C:LEU759 4.9 30.8 1.0 CB B:SER729 4.9 29.1 1.0

Chlorine binding site 4 out of 4 in the Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Lbd Conformation 3 (LBDCONF3) of GLUA2 Flip Q Isoform of Ampa Receptor in Complex with Gain-of-Function Tarp Gamma-2, with 150MM Nacl, 330UM Ctz, and 100MM Glutamate (Open-NA260) within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1302 b:81.7 occ:1.00 CL D:CYZ1302 0.0 81.7 1.0 C13 D:CYZ1302 1.8 52.1 1.0 C12 D:CYZ1302 2.7 48.6 1.0 C14 D:CYZ1302 2.8 49.9 1.0 O4 D:CYZ1302 3.0 53.6 1.0 S2 D:CYZ1302 3.2 62.5 1.0 CG D:ASP760 3.2 62.2 1.0 N D:ASP760 3.3 53.5 1.0 OD1 D:ASP760 3.3 62.5 1.0 OD2 D:ASP760 3.4 62.7 1.0 O D:HOH1402 3.5 39.8 1.0 N3 D:CYZ1302 3.5 48.4 1.0 CA D:ASP760 3.5 55.2 1.0 C D:LEU759 3.5 46.7 1.0 CB D:LEU759 3.6 45.3 1.0 O D:LEU759 3.9 49.0 1.0 CB D:ASP760 3.9 55.9 1.0 C11 D:CYZ1302 4.0 47.1 1.0 O D:PHE495 4.1 42.6 1.0 C10 D:CYZ1302 4.1 47.6 1.0 CA D:LEU759 4.2 45.6 1.0 C9 D:CYZ1302 4.6 44.7 1.0 CG D:LEU759 4.8 46.2 1.0 O3 D:CYZ1302 4.8 51.3 1.0 CD1 D:LEU759 4.8 43.7 1.0 C D:ASP760 4.9 59.6 1.0

T.Nakagawa, X.Wang, F.J.Miguez-Cabello, D.Bowie. Open Gate of Ampa Receptor Is A CA2+ Binding Site Critical to Ion Transport To Be Published.