Atomistry » Chlorine » PDB 8fph-8fvn » 8fup
Atomistry »
  Chlorine »
    PDB 8fph-8fvn »
      8fup »

Chlorine in PDB 8fup: Bromodomain of Cbp Liganded with Bms-536924 and Ccs-1477

Enzymatic activity of Bromodomain of Cbp Liganded with Bms-536924 and Ccs-1477

All present enzymatic activity of Bromodomain of Cbp Liganded with Bms-536924 and Ccs-1477:
2.3.1.48;

Protein crystallography data

The structure of Bromodomain of Cbp Liganded with Bms-536924 and Ccs-1477, PDB code: 8fup was solved by E.Schonbrunn, M.Bikowitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.11 / 1.70
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 42.95, 53.46, 110.31, 90, 90, 90
R / Rfree (%) 18.6 / 21.3

Other elements in 8fup:

The structure of Bromodomain of Cbp Liganded with Bms-536924 and Ccs-1477 also contains other interesting chemical elements:

Fluorine (F) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Bromodomain of Cbp Liganded with Bms-536924 and Ccs-1477 (pdb code 8fup). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Bromodomain of Cbp Liganded with Bms-536924 and Ccs-1477, PDB code: 8fup:

Chlorine binding site 1 out of 1 in 8fup

Go back to Chlorine Binding Sites List in 8fup
Chlorine binding site 1 out of 1 in the Bromodomain of Cbp Liganded with Bms-536924 and Ccs-1477


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Bromodomain of Cbp Liganded with Bms-536924 and Ccs-1477 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1201

b:14.4
occ:1.00
CL16 A:N6I1201 0.0 14.4 1.0
C15 A:N6I1201 1.8 11.5 1.0
C14 A:N6I1201 2.7 11.9 1.0
C17 A:N6I1201 2.7 11.2 1.0
O A:HOH1320 3.6 26.8 1.0
CH2 A:TRP1151 3.7 11.7 1.0
CG A:MET1193 3.8 11.1 1.0
CA A:ASP1190 3.9 13.9 1.0
CB A:MET1193 4.0 11.6 1.0
CZ3 A:TRP1151 4.0 11.4 1.0
C13 A:N6I1201 4.0 12.0 1.0
C11 A:N6I1201 4.0 11.3 1.0
CG2 A:ILE1189 4.2 11.7 1.0
O A:ILE1189 4.3 11.2 1.0
N A:ASP1190 4.3 11.3 1.0
C A:ILE1189 4.5 12.0 1.0
C12 A:N6I1201 4.5 12.1 1.0
CB A:ASP1190 4.6 15.3 1.0
OD1 A:ASP1190 4.7 23.4 1.0
O A:ASP1190 4.7 13.3 1.0
CG A:ASP1190 4.7 22.6 1.0
CG1 A:ILE1189 4.8 10.8 1.0
CZ2 A:TRP1151 4.8 11.9 1.0
C A:ASP1190 4.9 12.8 1.0

Reference:

E.Schonbrunn, M.Bikowitz. Structural Basis of Cbp and EP300 Interaction with Kinase Inhibitors To Be Published.
Page generated: Sun Jul 13 11:40:02 2025

Last articles

Mn in 9LJU
Mn in 9LJW
Mn in 9LJS
Mn in 9LJR
Mn in 9LJT
Mn in 9LJV
Mg in 9UA2
Mg in 9R96
Mg in 9VM1
Mg in 9P01
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy