Chlorine in PDB 8gv9: The Cryo-Em Structure of HAE2 with Chloride Ion

The binding sites of Chlorine atom in the The Cryo-Em Structure of HAE2 with Chloride Ion (pdb code 8gv9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Cryo-Em Structure of HAE2 with Chloride Ion, PDB code: 8gv9:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The Cryo-Em Structure of HAE2 with Chloride Ion


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Cryo-Em Structure of HAE2 with Chloride Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1301 b:74.5 occ:1.00 NE A:ARG1060 3.7 39.4 1.0 CB A:VAL1059 3.8 45.3 1.0 N A:ARG1060 3.8 35.6 1.0 NH2 A:ARG1060 3.9 38.0 1.0 N A:VAL1059 3.9 38.6 1.0 CB A:ALA1057 4.0 34.7 1.0 C A:ALA1057 4.1 39.2 1.0 CA A:ALA1057 4.1 38.3 1.0 CA A:VAL1059 4.2 42.7 1.0 CZ A:ARG1060 4.3 43.3 1.0 O A:ALA1057 4.3 40.5 1.0 CG2 A:VAL1059 4.3 43.9 1.0 CB A:ARG1060 4.4 30.7 1.0 N A:THR1058 4.5 33.1 1.0 C A:VAL1059 4.5 44.4 1.0 CG A:ARG1060 4.6 35.5 1.0 CA A:ARG1060 4.7 32.0 1.0 CD A:ARG1060 4.8 37.7 1.0 CG1 A:VAL1059 4.8 41.1 1.0 C A:THR1058 4.9 33.1 1.0

Chlorine binding site 2 out of 2 in the The Cryo-Em Structure of HAE2 with Chloride Ion


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Cryo-Em Structure of HAE2 with Chloride Ion within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1301 b:69.1 occ:1.00 NE B:ARG1060 3.7 37.8 1.0 CB B:VAL1059 3.7 41.8 1.0 NH2 B:ARG1060 3.7 36.3 1.0 N B:ARG1060 3.8 35.2 1.0 N B:VAL1059 3.9 36.9 1.0 CB B:ALA1057 4.1 33.8 1.0 C B:ALA1057 4.1 36.8 1.0 CA B:ALA1057 4.1 36.0 1.0 CZ B:ARG1060 4.2 41.3 1.0 CA B:VAL1059 4.2 40.7 1.0 O B:ALA1057 4.3 39.0 1.0 CG2 B:VAL1059 4.4 42.1 1.0 CB B:ARG1060 4.4 32.7 1.0 N B:THR1058 4.5 34.0 1.0 C B:VAL1059 4.5 41.5 1.0 CG B:ARG1060 4.6 35.0 1.0 CG1 B:VAL1059 4.6 36.1 1.0 CA B:ARG1060 4.7 31.8 1.0 CD B:ARG1060 4.8 36.1 1.0 C B:THR1058 4.9 29.3 1.0

Q.Zhang, L.Jian, D.Yao, B.Rao, Y.Xia, K.Hu, S.Li, Y.Shen, M.Cao, A.Qin, J.Zhao, Y.Cao. The Structural Basis of the pH-Homeostasis Mediated By the Cl - /Hco 3 - Exchanger, AE2. Nat Commun V. 14 1812 2023.
ISSN: ESSN 2041-1723
PubMed: 37002221
DOI: 10.1038/S41467-023-37557-Y