Chlorine in PDB 8hq4: B27 in Complex with CRM1-Ran-RANBP1

The structure of B27 in Complex with CRM1-Ran-RANBP1, PDB code: 8hq4 was solved by Y.Lei, Q.Sun, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.06 / 2.12
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	106.08, 106.08, 304, 90, 90, 90
R / Rfree (%)	18.7 / 21

The structure of B27 in Complex with CRM1-Ran-RANBP1 also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Fluorine	(F)	4 atoms

The binding sites of Chlorine atom in the B27 in Complex with CRM1-Ran-RANBP1 (pdb code 8hq4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the B27 in Complex with CRM1-Ran-RANBP1, PDB code: 8hq4:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the B27 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of B27 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1102 b:81.4 occ:1.00 O C:ARG325 3.4 41.5 1.0 N C:ALA328 3.7 44.9 1.0 N C:ARG327 3.8 42.4 1.0 C C:ARG325 3.8 43.0 1.0 O C:ALA324 3.9 44.8 1.0 CB C:ALA328 3.9 45.5 1.0 CG C:ARG327 4.0 44.4 1.0 O C:HOH1589 4.1 58.4 1.0 N C:ASN326 4.2 41.3 1.0 O C:LEU323 4.4 39.2 1.0 C C:ASN326 4.4 42.3 1.0 CA C:ALA328 4.4 45.4 1.0 O C:HOH1500 4.5 58.7 1.0 C C:ALA324 4.5 42.3 1.0 C C:ARG327 4.6 42.0 1.0 CA C:ARG327 4.6 44.1 1.0 CA C:ASN326 4.6 42.6 1.0 CA C:ARG325 4.7 45.0 1.0 NE C:ARG327 4.7 45.0 1.0 O C:HOH1462 4.7 65.9 1.0 CB C:ARG327 4.8 44.4 1.0 N C:ARG325 4.9 44.0 1.0 CZ C:ARG327 5.0 44.9 1.0

Chlorine binding site 2 out of 2 in the B27 in Complex with CRM1-Ran-RANBP1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of B27 in Complex with CRM1-Ran-RANBP1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1103 b:89.8 occ:1.00 NH1 C:ARG77 3.4 83.0 1.0 O C:LYS1040 4.0 46.9 1.0 C C:LYS1040 4.3 46.9 1.0 NE2 C:HIS1005 4.3 45.6 1.0 CD2 C:HIS1005 4.4 45.6 1.0 CG2 C:VAL1042 4.5 44.9 1.0 CZ C:ARG77 4.5 77.8 1.0 N C:GLU1041 4.5 45.2 1.0 CA C:GLU1041 4.6 46.1 1.0 C C:GLU1041 4.6 44.1 1.0 O C:HOH1581 4.6 68.0 1.0 CE1 C:HIS1005 4.6 44.3 1.0 O C:ARG77 4.7 54.7 1.0 O C:ILE1039 4.7 45.3 1.0 O C:GLU1041 4.7 43.2 1.0 CE C:LYS78 4.7 63.6 1.0 CG C:HIS1005 4.8 45.0 1.0 CB C:ARG77 4.8 59.9 1.0 ND1 C:HIS1005 4.9 45.0 1.0 N C:VAL1042 5.0 41.8 1.0

Y.Lei, Q.Sun. B27 in Complex with CRM1-Ran-RANBP1 To Be Published.