Atomistry » Chlorine » PDB 8h8q-8huv » 8huk
Atomistry »
  Chlorine »
    PDB 8h8q-8huv »
      8huk »

Chlorine in PDB 8huk: X-Ray Structure of Human Ppar Alpha Ligand Binding Domain- Lanifibranor-SRC1 Coactivator Peptide Co-Crystals Obtained By Soaking

Enzymatic activity of X-Ray Structure of Human Ppar Alpha Ligand Binding Domain- Lanifibranor-SRC1 Coactivator Peptide Co-Crystals Obtained By Soaking

All present enzymatic activity of X-Ray Structure of Human Ppar Alpha Ligand Binding Domain- Lanifibranor-SRC1 Coactivator Peptide Co-Crystals Obtained By Soaking:
2.3.1.48;

Protein crystallography data

The structure of X-Ray Structure of Human Ppar Alpha Ligand Binding Domain- Lanifibranor-SRC1 Coactivator Peptide Co-Crystals Obtained By Soaking, PDB code: 8huk was solved by S.Kamata, R.Ishikawa, M.Akahane, A.Honda, T.Oyama, I.Ishii, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.20 / 2.98
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 59.733, 101.383, 60.361, 90, 98.48, 90
R / Rfree (%) 19.7 / 25.4

Chlorine Binding Sites:

The binding sites of Chlorine atom in the X-Ray Structure of Human Ppar Alpha Ligand Binding Domain- Lanifibranor-SRC1 Coactivator Peptide Co-Crystals Obtained By Soaking (pdb code 8huk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the X-Ray Structure of Human Ppar Alpha Ligand Binding Domain- Lanifibranor-SRC1 Coactivator Peptide Co-Crystals Obtained By Soaking, PDB code: 8huk:

Chlorine binding site 1 out of 1 in 8huk

Go back to Chlorine Binding Sites List in 8huk
Chlorine binding site 1 out of 1 in the X-Ray Structure of Human Ppar Alpha Ligand Binding Domain- Lanifibranor-SRC1 Coactivator Peptide Co-Crystals Obtained By Soaking


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of Human Ppar Alpha Ligand Binding Domain- Lanifibranor-SRC1 Coactivator Peptide Co-Crystals Obtained By Soaking within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl501

b:90.6
occ:1.00
 CL1 C:BJB501 0.0 90.6 1.0
C7 C:BJB501 1.8 94.5 1.0
C8 C:BJB501 2.8 77.3 1.0
C6 C:BJB501 2.9 91.6 1.0
H1 C:BJB501 3.0 93.2 1.0
H9 C:BJB501 3.0 110.4 1.0
CG2 C:ILE272 3.9 64.1 1.0
CB C:PHE351 4.0 82.9 1.0
CD1 C:PHE351 4.0 79.3 1.0
CD1 C:LEU347 4.1 77.4 1.0
C9 C:BJB501 4.2 111.6 1.0
CD1 C:ILE354 4.2 78.2 1.0
O C:GLU269 4.3 94.0 1.0
C4 C:BJB501 4.3 95.3 1.0
O C:PHE351 4.4 80.6 1.0
CG C:PHE351 4.4 74.1 1.0
N C:PHE273 4.4 76.1 1.0
CB C:ILE272 4.4 74.4 1.0
CA C:PHE273 4.5 85.8 1.0
CA C:PHE351 4.6 86.9 1.0
C C:PHE351 4.7 82.2 1.0
CB C:PHE273 4.7 92.2 1.0
C5 C:BJB501 4.8 120.3 1.0
C C:ILE272 4.9 72.5 1.0
H2 C:BJB501 5.0 134.3 1.0
CE1 C:PHE351 5.0 88.1 1.0

Reference:

S.Kamata, A.Honda, R.Ishikawa, M.Akahane, A.Fujita, C.Kaneko, S.Miyawaki, Y.Habu, Y.Shiiyama, K.Uchii, Y.Machida, T.Oyama, I.Ishii. Functional and Structural Insights Into the Human Ppar Alpha / Delta / Gamma Targeting Preferences of Anti-Nash Investigational Drugs, Lanifibranor, Seladelpar, and Elafibranor Antioxidants V. 12 1523 2023.
ISSN: ESSN 2076-3921
DOI: 10.3390/ANTIOX12081523
Page generated: Sun Jul 13 12:07:25 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy