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Chlorine in PDB 8iyx: Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365 (pdb code 8iyx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365, PDB code: 8iyx:

Chlorine binding site 1 out of 1 in 8iyx

Go back to Chlorine Binding Sites List in 8iyx
Chlorine binding site 1 out of 1 in the Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of the GPR34 Receptor in Complex with the Antagonist Yl-365 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl401

b:82.8
occ:1.00
CL36 C:S6R401 0.0 82.8 1.0
C35 C:S6R401 1.8 82.8 1.0
C37 C:S6R401 2.7 82.8 1.0
C34 C:S6R401 2.8 82.8 1.0
C31 C:S6R401 4.0 82.8 1.0
C33 C:S6R401 4.1 82.8 1.0
CA C:GLY131 4.4 65.8 1.0
C32 C:S6R401 4.6 82.8 1.0
CE2 C:TYR135 4.6 62.4 1.0
C C:GLY131 4.6 65.8 1.0
N C:THR132 4.9 62.3 1.0
CD2 C:TYR135 4.9 62.4 1.0
NH2 C:ARG208 5.0 124.9 1.0

Reference:

A.Xia, X.Yong, C.Zhang, G.Lin, G.Jia, C.Zhao, X.Wang, Y.Hao, Y.Wang, P.Zhou, X.Yang, Y.Deng, C.Wu, Y.Chen, J.Zhu, X.Tang, J.Liu, S.Zhang, J.Zhang, Z.Xu, Q.Hu, J.Zhao, Y.Yue, W.Yan, Z.Su, Y.Wei, R.Zhou, H.Dong, Z.Shao, S.Yang. Cryo-Em Structures of Human GPR34 Enable the Identification of Selective Antagonists. Proc.Natl.Acad.Sci.Usa V. 120 35120 2023.
ISSN: ESSN 1091-6490
PubMed: 37733739
DOI: 10.1073/PNAS.2308435120
Page generated: Sun Jul 13 12:32:04 2025

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