Chlorine in PDB 8j6j: Cryo-Em Structure of Thehydroxycarboxylic Acid Receptor 2-Gi Protein Complex Bound with GSK256073

The binding sites of Chlorine atom in the Cryo-Em Structure of Thehydroxycarboxylic Acid Receptor 2-Gi Protein Complex Bound with GSK256073 (pdb code 8j6j). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of Thehydroxycarboxylic Acid Receptor 2-Gi Protein Complex Bound with GSK256073, PDB code: 8j6j:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of Thehydroxycarboxylic Acid Receptor 2-Gi Protein Complex Bound with GSK256073


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of Thehydroxycarboxylic Acid Receptor 2-Gi Protein Complex Bound with GSK256073 within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl501 b:96.6 occ:1.00 CL17 R:OKL501 0.0 96.6 1.0 C15 R:OKL501 1.8 87.3 1.0 N14 R:OKL501 2.8 87.0 1.0 N16 R:OKL501 2.8 77.4 1.0 O R:CYS177 2.8 87.3 1.0 CZ3 R:TRP91 3.3 87.6 1.0 C R:CYS177 3.4 85.8 1.0 CA R:SER178 3.6 71.3 1.0 CH2 R:TRP91 3.8 90.6 1.0 N R:SER178 3.8 76.6 1.0 CD2 R:LEU83 3.8 89.9 1.0 C13 R:OKL501 3.9 76.9 1.0 C12 R:OKL501 3.9 75.6 1.0 CE R:MET103 4.0 88.2 1.0 CB R:SER178 4.1 75.2 1.0 CB R:CYS177 4.2 87.8 1.0 CD2 R:LEU104 4.3 76.6 1.0 SG R:CYS177 4.3 96.3 1.0 CA R:CYS177 4.4 84.6 1.0 CE3 R:TRP91 4.4 86.0 1.0 ND2 R:ASN86 4.7 88.6 1.0 C R:SER178 4.8 71.2 1.0

S.Zhu, Q.Yuan, X.Li, X.He, S.Shen, D.Wang, J.Li, X.Cheng, X.Duan, H.E.Xu, J.Duan. Molecular Recognition of Niacin and Lipid-Lowering Drugs By the Human Hydroxycarboxylic Acid Receptor 2. Cell Rep V. 42 13406 2023.
ISSN: ESSN 2211-1247
PubMed: 37952153
DOI: 10.1016/J.CELREP.2023.113406