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Chlorine in PDB 8olr: Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A
Enzymatic activity of Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A
All present enzymatic activity of Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A:
3.4.25.1;
3.4.25.1;
Protein crystallography data
The structure of Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A, PDB code: 8olr
was solved by
A.Illigmann,
M.-T.Vielberg,
M.Lakemeyer,
F.Wolf,
N.Staudt,
T.Dema,
P.Stange,
I.Malik,
S.Grond,
S.A.Sieber,
M.Groll,
L.Kaysser,
H.Broetz-Oesterhelt,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 15.00 / 2.80 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 136.96, 302.05, 146.01, 90, 113.09, 90 |
| R / Rfree (%) | 18.2 / 20.8 |
Other elements in 8olr:
The structure of Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A also contains other interesting chemical elements:
| Magnesium | (Mg) | 7 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A
(pdb code 8olr). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A, PDB code: 8olr:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A, PDB code: 8olr:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 8olr
Go back to
Chlorine Binding Sites List in 8olr
Chlorine binding site 1 out
of 2 in the Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 8olr
Go back to
Chlorine Binding Sites List in 8olr
Chlorine binding site 2 out
of 2 in the Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Structure of Yeast 20S Proteasome in Complex with the Natural Product Beta-Lactone Inhibitor Cystargolide A within 5.0Å range:
|
Reference:
A.Illigmann,
M.T.Vielberg,
M.Lakemeyer,
F.Wolf,
T.Dema,
P.Stange,
W.Kuttenlochner,
E.Liebhart,
A.Kulik,
N.Staudt,
I.Malik,
S.Grond,
S.A.Sieber,
L.Kaysser,
M.Groll,
H.Brotz-Oesterhelt.
Structure of Staphylococcus Aureus Clpp Bound to the Covalent Active Site Inhibitor Cystargolide A. Angew.Chem.Int.Ed.Engl. 14028 2023.
ISSN: ESSN 1521-3773
PubMed: 38029352
DOI: 10.1002/ANIE.202314028
Page generated: Sun Jul 13 12:51:33 2025
ISSN: ESSN 1521-3773
PubMed: 38029352
DOI: 10.1002/ANIE.202314028
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