Chlorine in PDB 8ox3: Structure of the Murine Lyve-1 (Lymphatic Vessel Endothelial Receptor- 1) Hyaluronan Binding Domain Bound with Octasaccharide Hyaluronan.

The structure of Structure of the Murine Lyve-1 (Lymphatic Vessel Endothelial Receptor- 1) Hyaluronan Binding Domain Bound with Octasaccharide Hyaluronan., PDB code: 8ox3 was solved by T.Ni, N.Bannerji, D.J.Jackson, R.J.C.Gilbert, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.90 / 1.05
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	86.107, 56.963, 30.908, 90, 106.27, 90
R / Rfree (%)	15.1 / 16.3

The binding sites of Chlorine atom in the Structure of the Murine Lyve-1 (Lymphatic Vessel Endothelial Receptor- 1) Hyaluronan Binding Domain Bound with Octasaccharide Hyaluronan. (pdb code 8ox3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of the Murine Lyve-1 (Lymphatic Vessel Endothelial Receptor- 1) Hyaluronan Binding Domain Bound with Octasaccharide Hyaluronan., PDB code: 8ox3:

Chlorine binding site 1 out of 1 in the Structure of the Murine Lyve-1 (Lymphatic Vessel Endothelial Receptor- 1) Hyaluronan Binding Domain Bound with Octasaccharide Hyaluronan.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Murine Lyve-1 (Lymphatic Vessel Endothelial Receptor- 1) Hyaluronan Binding Domain Bound with Octasaccharide Hyaluronan. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl407 b:32.1 occ:1.00 O A:ASN129 2.7 6.2 1.0 O A:ASP132 2.8 8.6 1.0 C1 A:PEG404 3.1 33.7 1.0 O A:SER130 3.2 11.0 1.0 C A:SER130 3.2 8.9 1.0 C2 A:PEG404 3.2 31.1 1.0 CA A:SER130 3.4 8.9 1.0 N A:ASP132 3.4 7.0 1.0 C A:ASP132 3.7 6.8 1.0 C A:ASN129 3.7 5.8 1.0 CE1 A:HIS128 3.8 10.0 1.0 O2 A:PEG404 3.8 33.6 1.0 CB A:ASP132 3.8 7.1 1.0 CA A:ASP132 3.8 6.7 1.0 N A:SER131 3.9 7.6 1.0 O A:HOH505 3.9 43.1 1.0 NE2 A:HIS128 4.0 9.8 1.0 N A:SER130 4.0 6.4 1.0 C A:SER131 4.2 7.6 1.0 O1 A:PEG404 4.3 35.0 1.0 C4 A:PEG405 4.3 50.6 1.0 CA A:SER131 4.6 8.1 1.0 O4 A:PEG405 4.6 50.3 1.0 CB A:SER130 4.6 11.1 1.0 C3 A:PEG404 4.7 31.6 1.0 CA A:GLY39 4.7 4.9 1.0 ND1 A:HIS128 4.8 8.8 1.0 N A:THR133 5.0 7.0 1.0 O A:SER131 5.0 8.8 1.0

F.Bano, S.Bannerji, T.Ni, D.E.Green, P.L.Deangelis, E.Paci, M.Lepsik, R.J.C.Gilbert, R.P.Richter, D.J.Jackson. A Novel Sliding Interaction with Hyaluronan Underlies the Mode of Action of Lyve-1, the Receptor For Leucocyte Entry and Trafficking in the Lymphatics To Be Published.