Chlorine in PDB 8qeh: Crystal Structure of the G11 Protein Heterotrimer Bound to FR900359 Inhibitor

The structure of Crystal Structure of the G11 Protein Heterotrimer Bound to FR900359 Inhibitor, PDB code: 8qeh was solved by J.Muehle, M.J.Rodrigues, R.Guixa-Gonzalez, X.Deupi, G.F.X.Schertler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	63.11 / 1.43
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	72.644, 95.813, 126.801, 90, 90, 90
R / Rfree (%)	14 / 18

The structure of Crystal Structure of the G11 Protein Heterotrimer Bound to FR900359 Inhibitor also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of the G11 Protein Heterotrimer Bound to FR900359 Inhibitor (pdb code 8qeh). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the G11 Protein Heterotrimer Bound to FR900359 Inhibitor, PDB code: 8qeh:

Chlorine binding site 1 out of 1 in the Crystal Structure of the G11 Protein Heterotrimer Bound to FR900359 Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the G11 Protein Heterotrimer Bound to FR900359 Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl407 b:23.2 occ:1.00 ZN A:ZN406 2.2 21.0 1.0 O A:HOH769 3.5 28.8 1.0 OG1 A:THR347 3.5 22.5 1.0 NE2 A:HIS327 3.6 21.2 1.0 CB A:TYR325 3.6 19.6 1.0 CB A:THR347 3.6 20.8 1.0 CG2 A:THR347 3.7 23.2 1.0 CD1 A:ILE270 3.8 32.0 1.0 CG2 A:VAL344 3.9 17.9 1.0 CA A:VAL344 3.9 17.8 1.0 CD2 A:HIS327 4.0 18.4 1.0 CG A:TYR325 4.0 20.0 1.0 CB A:VAL344 4.2 16.9 1.0 CG2 A:ILE270 4.3 22.2 1.0 CG1 A:VAL344 4.3 19.2 1.0 CD2 A:TYR325 4.6 24.1 1.0 CD1 A:TYR325 4.6 23.9 1.0 CG1 A:ILE270 4.6 27.7 1.0 O A:VAL344 4.6 17.6 1.0 N A:VAL344 4.7 15.8 1.0 CE1 A:HIS327 4.7 20.3 1.0 C A:VAL344 4.8 16.5 1.0 O A:ALA343 4.8 16.8 1.0 CA A:TYR325 4.9 19.9 1.0

J.Muehle, G.F.X.Schertler. Structure of the Heterotrimeric G11 Protein Bound to the Cyclic Depsipeptides FR900359 and Ym-254890 To Be Published.