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Chlorine in PDB 8t68: Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111
Enzymatic activity of Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111
All present enzymatic activity of Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111:
2.1.1.361; 2.1.1.362;
2.1.1.361; 2.1.1.362;
Protein crystallography data
The structure of Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111, PDB code: 8t68
was solved by
H.Zeng,
A.Dong,
P.J.Brown,
C.H.Arrowsmith,
A.M.Edwards,
L.Halabelian,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 40.76 / 1.90 |
| Space group | P 2 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 36.149, 75.528, 96.807, 90, 90, 90 |
| R / Rfree (%) | 22.6 / 26.4 |
Other elements in 8t68:
The structure of Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111 also contains other interesting chemical elements:
| Zinc | (Zn) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111
(pdb code 8t68). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111, PDB code: 8t68:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111, PDB code: 8t68:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 8t68
Go back to
Chlorine Binding Sites List in 8t68
Chlorine binding site 1 out
of 2 in the Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111 within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 8t68
Go back to
Chlorine Binding Sites List in 8t68
Chlorine binding site 2 out
of 2 in the Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Crystal Structure of the Set Domain of Human Histone-Lysine N- Methyltransferase SUV420H1 in Complex with RQ3-111 within 5.0Å range:
|
Reference:
H.Zeng,
A.Dong,
P.J.Brown,
C.H.Arrowsmith,
A.M.Edwards,
L.Halabelian,
Structural Genomics Consortium (Sgc).
Crystal Structure of the Set Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 in Complex with RQ3-111. To Be Published.
Page generated: Sun Jul 13 14:22:12 2025
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