Chlorine in PDB 8vr8: Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-B-Clm

The binding sites of Chlorine atom in the Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-B-Clm (pdb code 8vr8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-B-Clm, PDB code: 8vr8:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-B-Clm


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-B-Clm within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl3201 b:92.5 occ:1.00 CL1 A:CLM3201 0.0 92.5 1.0 C1 A:CLM3201 1.8 21.1 1.0 C2 A:CLM3201 2.7 52.8 1.0 CL2 A:CLM3201 2.9 72.0 1.0 C8 A:A2727 3.0 0.5 1.0 N2 A:CLM3201 3.2 2.1 1.0 N7 A:A2727 3.4 2.1 1.0 O2 A:CLM3201 3.6 68.2 1.0 N6 A:A2286 4.0 0.1 1.0 N9 A:A2727 4.2 2.7 1.0 O4 A:CLM3201 4.2 42.5 1.0 O5' A:G2729 4.4 4.8 1.0 OP2 A:G2729 4.4 7.3 1.0 C3 A:CLM3201 4.5 18.8 1.0 O4' A:G2729 4.5 4.5 1.0 O2' A:A2727 4.5 4.8 1.0 C5 A:A2727 4.7 9.1 1.0 C1' A:A2727 4.8 8.0 1.0 P A:G2729 5.0 7.2 1.0 C4 A:CLM3201 5.0 37.5 1.0

Chlorine binding site 2 out of 2 in the Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-B-Clm


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-B-Clm within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl3201 b:72.0 occ:1.00 CL2 A:CLM3201 0.0 72.0 1.0 C1 A:CLM3201 1.8 21.1 1.0 C2 A:CLM3201 2.7 52.8 1.0 O4' A:G2729 2.8 4.5 1.0 CL1 A:CLM3201 2.9 92.5 1.0 C1' A:G2729 3.1 6.8 1.0 N2 A:CLM3201 3.2 2.1 1.0 C4' A:G2729 3.4 8.1 1.0 O2' A:G2729 3.4 4.9 1.0 O2 A:CLM3201 3.6 68.2 1.0 C2' A:G2729 3.8 7.2 1.0 O5' A:G2729 4.2 4.8 1.0 C3' A:G2729 4.3 11.3 1.0 N9 A:G2729 4.3 3.2 1.0 C11 A:CLM3201 4.3 9.8 1.0 C5' A:G2729 4.4 10.9 1.0 C3 A:CLM3201 4.5 18.8 1.0 C10 A:CLM3201 4.9 21.6 1.0 C6 A:CLM3201 4.9 9.2 1.0

S.Majumdar, A.Kashyap, R.K.Koripella, M.R.Sharma, K.Hurst-Hess, S.R.Manjari, N.K.Banavali, P.Ghosh, R.K.Agrawal. Hflx-Mediated Drug Resistance Through Ribosome Splitting and Rrna Disordering in Mycobacteria. Proc.Natl.Acad.Sci.Usa V. 122 26122 2025.
ISSN: ESSN 1091-6490
PubMed: 39913204
DOI: 10.1073/PNAS.2419826122