Chlorine in PDB 8vrl: Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-A-Clm

The binding sites of Chlorine atom in the Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-A-Clm (pdb code 8vrl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-A-Clm, PDB code: 8vrl:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-A-Clm


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-A-Clm within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl3201 b:92.5 occ:1.00 CL1 A:CLM3201 0.0 92.5 1.0 C1 A:CLM3201 1.7 21.1 1.0 C2 A:CLM3201 2.7 52.8 1.0 O2 A:CLM3201 2.9 68.2 1.0 CL2 A:CLM3201 3.0 72.0 1.0 N6 A:A2286 3.7 1.7 1.0 C8 A:A2727 3.7 4.1 1.0 N 4:GLY197 3.7 29.2 1.0 N2 A:CLM3201 3.9 2.1 1.0 N7 A:A2727 3.9 1.1 1.0 CA 4:GLY196 4.0 49.0 1.0 NH2 4:ARG201 4.3 33.2 1.0 C 4:GLY196 4.3 48.0 1.0 N 4:GLY196 4.3 51.5 1.0 C6 A:A2286 4.7 3.3 1.0 O4' A:G2729 4.7 12.4 1.0 CA 4:GLY197 4.7 34.7 1.0 NE 4:ARG201 4.8 34.5 1.0 N1 A:A2286 4.8 7.9 1.0 N9 A:A2727 4.9 6.7 1.0 O4 A:CLM3201 5.0 42.5 1.0

Chlorine binding site 2 out of 2 in the Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-A-Clm


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Mycobacterium Smegmatis 50S Ribosomal Subunit Bound to Hflx and Chloramphenicol:50S-Hflx-A-Clm within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl3201 b:72.0 occ:1.00 CL2 A:CLM3201 0.0 72.0 1.0 C1 A:CLM3201 1.7 21.1 1.0 C2 A:CLM3201 2.7 52.8 1.0 N2 A:CLM3201 2.9 2.1 1.0 CL1 A:CLM3201 3.0 92.5 1.0 NE 4:ARG201 3.1 34.5 1.0 O2 A:CLM3201 3.7 68.2 1.0 CD 4:ARG201 3.7 31.7 1.0 CZ 4:ARG201 4.1 37.3 1.0 C3 A:CLM3201 4.1 18.8 1.0 NH2 4:ARG201 4.2 33.2 1.0 C11 A:CLM3201 4.2 9.8 1.0 O2' A:G2729 4.2 12.9 1.0 O4' A:G2729 4.3 12.4 1.0 CG 4:ARG201 4.3 37.4 1.0 N6 A:A2286 4.5 1.7 1.0 C6 A:CLM3201 4.5 9.2 1.0 C1' A:G2729 4.5 5.6 1.0 C5 A:CLM3201 4.7 7.6 1.0 C10 A:CLM3201 4.7 21.6 1.0 O5 A:CLM3201 4.7 16.8 1.0 C4' A:G2729 4.7 7.7 1.0 C2' A:G2729 5.0 8.7 1.0

S.Majumdar, A.Kashyap, R.K.Koripella, M.R.Sharma, K.Hurst-Hess, S.R.Manjari, N.K.Banavali, P.Ghosh, R.K.Agrawal. Hflx-Mediated Drug Resistance Through Ribosome Splitting and Rrna Disordering in Mycobacteria. Proc.Natl.Acad.Sci.Usa V. 122 26122 2025.
ISSN: ESSN 1091-6490
PubMed: 39913204
DOI: 10.1073/PNAS.2419826122