Atomistry » Chlorine » PDB 8vu4-8w8v » 8vui
Atomistry »
  Chlorine »
    PDB 8vu4-8w8v »
      8vui »

Chlorine in PDB 8vui: Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor

Protein crystallography data

The structure of Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor, PDB code: 8vui was solved by A.U.Singer, H.A.Bruce, L.Blazer, J.J.Adams, S.S.Sidhu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 98.51 / 2.10
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 56.39, 71.93, 197.02, 90, 90, 90
R / Rfree (%) 19.7 / 24

Other elements in 8vui:

The structure of Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor also contains other interesting chemical elements:

Sodium (Na) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor (pdb code 8vui). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor, PDB code: 8vui:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 8vui

Go back to Chlorine Binding Sites List in 8vui
Chlorine binding site 1 out of 6 in the Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl304

b:60.7
occ:1.00
 N A:VAL135 3.2 31.0 1.0
O A:VAL135 3.7 36.4 1.0
CA A:SER134 3.9 35.8 1.0
C A:SER134 4.0 37.6 1.0
CA A:VAL135 4.1 33.2 1.0
CB A:VAL135 4.2 37.2 1.0
C A:VAL135 4.3 32.9 1.0
CG1 A:VAL221 4.5 37.1 1.0
O A:PRO133 4.5 42.1 1.0
CB A:SER134 4.6 43.2 1.0
CG2 A:VAL135 4.6 33.7 1.0
CG2 A:VAL221 4.9 37.2 1.0

Chlorine binding site 2 out of 6 in 8vui

Go back to Chlorine Binding Sites List in 8vui
Chlorine binding site 2 out of 6 in the Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl305

b:76.4
occ:1.00
 NZ A:LYS224 3.0 57.8 1.0
OG1 A:THR207 3.8 53.2 1.0
CE A:LYS224 4.1 59.2 1.0
O A:GLN206 4.2 50.0 1.0
NA A:NA303 4.3 54.7 1.0
O A:GLY204 4.3 72.4 1.0
C A:GLN206 4.5 48.7 1.0
O A:HOH422 4.5 36.8 1.0
CA A:THR207 4.5 43.6 1.0
N A:THR207 4.7 48.7 1.0
O A:THR205 4.7 68.0 1.0
O A:LEU203 4.7 57.0 1.0
CB A:THR207 4.8 44.8 1.0
C A:THR205 4.8 67.4 1.0
C A:GLY204 4.8 71.9 1.0

Chlorine binding site 3 out of 6 in 8vui

Go back to Chlorine Binding Sites List in 8vui
Chlorine binding site 3 out of 6 in the Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor within 5.0Å range:
probe atom residue distance (Å) B Occ
G:Cl305

b:78.5
occ:1.00
 N G:SER188 2.9 54.7 1.0
CA G:ASP187 3.6 45.4 1.0
CB G:SER188 3.6 68.8 1.0
O G:GLN186 3.7 45.3 1.0
C G:ASP187 3.7 55.5 1.0
OG G:SER188 3.8 81.4 1.0
CA G:SER188 3.9 61.2 1.0
OD1 G:ASP187 4.2 56.1 1.0
CG G:ASP187 4.4 51.7 1.0
C G:GLN186 4.5 41.6 1.0
N G:ASP187 4.5 45.7 1.0
CB G:ASP187 4.6 46.7 1.0
O G:ASP187 4.9 55.2 1.0
OD2 G:ASP187 5.0 54.2 1.0

Chlorine binding site 4 out of 6 in 8vui

Go back to Chlorine Binding Sites List in 8vui
Chlorine binding site 4 out of 6 in the Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl304

b:72.9
occ:1.00
 N D:HIS114 3.2 57.1 1.0
CA D:ILE113 3.4 56.1 1.0
CB D:ILE113 3.7 53.7 1.0
CG2 D:ILE113 3.7 54.1 1.0
C D:ILE113 3.8 58.0 1.0
O D:HIS114 4.0 47.6 1.0
CB D:GLU117 4.0 58.5 1.0
O D:VAL112 4.2 53.2 1.0
CA D:HIS114 4.3 61.8 1.0
CG1 D:VAL118 4.3 52.1 1.0
CB D:HIS114 4.5 59.1 1.0
ND1 D:HIS114 4.5 66.5 1.0
C D:HIS114 4.6 54.3 1.0
N D:ILE113 4.6 52.7 1.0
CG D:GLU117 4.8 63.3 1.0
NH1 D:ARG111 4.9 52.4 1.0
C D:VAL112 4.9 54.2 1.0
CG D:HIS114 5.0 61.4 1.0

Chlorine binding site 5 out of 6 in 8vui

Go back to Chlorine Binding Sites List in 8vui
Chlorine binding site 5 out of 6 in the Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl305

b:60.3
occ:0.52
 CL D:CL305 0.0 60.3 0.5
CL D:CL305 2.1 60.4 0.5
N D:ASP122 2.8 49.9 1.0
OG1 D:THR148 3.0 73.3 1.0
CG D:ASP122 3.5 57.5 1.0
CB D:ASP122 3.5 52.8 1.0
CB D:PRO145 3.7 54.8 1.0
CA D:LEU121 3.7 48.7 1.0
C D:LEU121 3.7 52.1 1.0
CA D:ASP122 3.7 51.5 1.0
CG2 D:THR148 3.7 70.0 1.0
CB D:LEU121 3.7 51.4 1.0
OD1 D:ASP122 3.8 58.1 1.0
OD2 D:ASP122 3.9 57.4 1.0
CB D:THR148 3.9 74.5 1.0
CD2 D:LEU121 4.0 50.7 1.0
O D:PRO146 4.2 65.1 1.0
NZ D:LYS14 4.3 57.2 1.0
CG D:PRO145 4.4 52.3 1.0
CG D:LEU121 4.5 54.4 1.0
O D:ASP122 4.6 49.7 1.0
O D:GLU31 4.6 62.8 1.0
C D:ASP122 4.6 54.6 1.0
O D:GLU147 4.7 73.4 1.0
NH2 D:ARG32 4.8 68.6 0.5
CA D:THR148 4.9 77.4 1.0
CZ D:ARG32 4.9 65.6 0.5
CA D:PRO145 4.9 56.8 1.0
O D:LEU121 4.9 50.2 1.0
NH1 D:ARG32 5.0 65.9 0.5
C D:PRO145 5.0 55.0 1.0

Chlorine binding site 6 out of 6 in 8vui

Go back to Chlorine Binding Sites List in 8vui
Chlorine binding site 6 out of 6 in the Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Structure of FABS1CE-Epr-1, An Elbow-Locked Fab, in Complex with the Erythropoeitin Receptor within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl305

b:60.4
occ:0.48
 CL D:CL305 0.0 60.4 0.5
CL D:CL305 2.1 60.3 0.5
NZ D:LYS14 3.0 57.2 1.0
O D:GLU31 3.2 62.8 1.0
NH1 D:ARG32 3.4 65.9 0.5
N D:ASP122 3.5 49.9 1.0
OD1 D:ASP122 3.5 58.1 1.0
CA D:LEU121 3.8 48.7 1.0
CZ D:ARG32 3.8 65.6 0.5
C D:GLU31 3.9 58.1 1.0
CG D:ASP122 3.9 57.5 1.0
CB D:GLU31 3.9 60.0 1.0
C D:LEU121 4.0 52.1 1.0
O D:LEU120 4.0 51.3 1.0
CA D:GLU31 4.1 56.2 1.0
OE1 D:GLU31 4.1 55.3 1.0
NH2 D:ARG32 4.2 68.6 0.5
OD2 D:ASP122 4.3 57.4 1.0
CG D:ARG32 4.5 65.8 0.5
NE D:ARG32 4.5 66.7 0.5
CD2 D:LEU121 4.5 50.7 1.0
CE D:LYS14 4.5 54.0 1.0
CB D:ASP122 4.5 52.8 1.0
CB D:LEU121 4.5 51.4 1.0
CA D:ASP122 4.5 51.5 1.0
CG D:GLU31 4.6 58.7 1.0
OG1 D:THR148 4.7 73.3 1.0
CG D:ARG32 4.7 64.0 0.5
N D:LEU121 4.8 51.0 1.0
C D:LEU120 4.8 51.2 1.0
CD D:ARG32 4.8 65.5 0.5
CD D:GLU31 4.9 62.9 1.0
N D:ARG32 4.9 58.9 0.5
N D:ARG32 4.9 58.9 0.5
CG2 D:THR148 4.9 70.0 1.0

Reference:

H.A.Bruce, A.U.Singer, L.L.Blazer, K.Luu, L.Ploder, A.Pavlenco, I.Kurinov, J.J.Adams, S.S.Sidhu. Antigen-Binding Fragments with Improved Crystal Lattice Packing and Enhanced Conformational Flexibility at the Elbow Region As Crystallization Chaperones. Protein Sci. V. 33 E5081 2024.
ISSN: ESSN 1469-896X
PubMed: 38924648
DOI: 10.1002/PRO.5081
Page generated: Sun Jul 13 15:23:57 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy