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Atomistry » Chlorine » PDB 8wby-8wtr » 8wd4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8wby-8wtr » 8wd4 » |
Chlorine in PDB 8wd4: Egfr(L858R/T790/C797S) in Complex with Compound 5JProtein crystallography data
The structure of Egfr(L858R/T790/C797S) in Complex with Compound 5J, PDB code: 8wd4
was solved by
Y.Nishikawa,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8wd4:
The structure of Egfr(L858R/T790/C797S) in Complex with Compound 5J also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Egfr(L858R/T790/C797S) in Complex with Compound 5J
(pdb code 8wd4). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Egfr(L858R/T790/C797S) in Complex with Compound 5J, PDB code: 8wd4: Chlorine binding site 1 out of 1 in 8wd4Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Egfr(L858R/T790/C797S) in Complex with Compound 5J
![]() Mono view ![]() Stereo pair view
Reference:
H.Kageji,
T.Momose,
Y.Nagamoto,
N.Togashi,
I.Yasumatsu,
Y.Nishikawa,
K.Kihara,
K.Hiramoto,
M.Minami,
N.Kasanuki,
T.Isoyama,
H.Naito.
Synthesis, Activity, and Their Relationships of 2,4-Diaminonicotinamide Derivatives As Egfr Inhibitors Targeting C797S Mutation. Bioorg.Med.Chem.Lett. 29575 2023.
Page generated: Sun Jul 13 15:32:12 2025
ISSN: ESSN 1464-3405 PubMed: 38065292 DOI: 10.1016/J.BMCL.2023.129575 |
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