Chlorine in PDB 8wpm: Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145

The structure of Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145 also contains other interesting chemical elements:

Fluorine	(F)	12 atoms
Calcium	(Ca)	3 atoms
Zinc	(Zn)	4 atoms

The binding sites of Chlorine atom in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145 (pdb code 8wpm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145, PDB code: 8wpm:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl801 b:67.5 occ:1.00 CL1 A:PJQ801 0.0 67.5 1.0 C24 A:PJQ801 1.8 43.6 1.0 C23 A:PJQ801 2.7 45.7 1.0 C26 A:PJQ801 2.7 42.6 1.0 C22 A:PJQ801 4.0 44.3 1.0 C27 A:PJQ801 4.0 40.2 1.0 CG1 A:ILE588 4.1 36.9 1.0 C21 A:PJQ801 4.5 38.8 1.0 CD1 A:ILE588 4.6 39.6 1.0

Chlorine binding site 2 out of 4 in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1001 b:52.0 occ:1.00 CL1 B:PJQ1001 0.0 52.0 1.0 C24 B:PJQ1001 1.8 43.9 1.0 C26 B:PJQ1001 2.7 31.3 1.0 C23 B:PJQ1001 2.8 43.3 1.0 CE2 B:PHE565 3.8 42.8 1.0 CD1 B:LEU568 3.9 32.7 1.0 C27 B:PJQ1001 4.0 33.9 1.0 C22 B:PJQ1001 4.0 34.2 1.0 CD2 B:PHE565 4.2 41.7 1.0 C21 B:PJQ1001 4.5 34.4 1.0 CZ B:PHE565 4.9 43.4 1.0

Chlorine binding site 3 out of 4 in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1001 b:57.6 occ:1.00 CL1 C:PJQ1001 0.0 57.6 1.0 C24 C:PJQ1001 1.8 35.6 1.0 C26 C:PJQ1001 2.7 30.5 1.0 C23 C:PJQ1001 2.8 41.8 1.0 CE1 C:PHE565 3.6 35.0 1.0 CD1 C:PHE565 3.8 36.1 1.0 C27 C:PJQ1001 4.0 33.4 1.0 C22 C:PJQ1001 4.0 39.1 1.0 CD1 C:LEU568 4.1 25.1 1.0 C21 C:PJQ1001 4.6 30.9 1.0 CZ C:PHE565 4.8 37.8 1.0

Chlorine binding site 4 out of 4 in the Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Cryo-Em Structure of the Human TRPC1/C4 Heteromer in Complex with PICO145 within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1001 b:64.0 occ:1.00 CL1 D:PJQ1001 0.0 64.0 1.0 C24 D:PJQ1001 1.8 43.3 1.0 C26 D:PJQ1001 2.7 33.4 1.0 C23 D:PJQ1001 2.7 40.8 1.0 CE1 D:PHE565 3.9 33.2 1.0 C27 D:PJQ1001 4.0 29.7 1.0 C22 D:PJQ1001 4.0 31.5 1.0 CD1 D:PHE565 4.1 31.0 1.0 CD1 D:LEU568 4.3 17.9 1.0 C21 D:PJQ1001 4.5 27.9 1.0

J.Won, H.Jeong, H.H.Lee. Structure of A Trp Channel To Be Published.