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Atomistry » Chlorine » PDB 8za8-9auv » 8zbu | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 8za8-9auv » 8zbu » |
Chlorine in PDB 8zbu: Cryo-Em Structure of Nanodisc-Reconstituted Human MRP4 WITHE1202Q Mutation (in Complex with Lapatinib)Enzymatic activity of Cryo-Em Structure of Nanodisc-Reconstituted Human MRP4 WITHE1202Q Mutation (in Complex with Lapatinib)
All present enzymatic activity of Cryo-Em Structure of Nanodisc-Reconstituted Human MRP4 WITHE1202Q Mutation (in Complex with Lapatinib):
7.6.2.2; 7.6.2.3; Other elements in 8zbu:
The structure of Cryo-Em Structure of Nanodisc-Reconstituted Human MRP4 WITHE1202Q Mutation (in Complex with Lapatinib) also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Cryo-Em Structure of Nanodisc-Reconstituted Human MRP4 WITHE1202Q Mutation (in Complex with Lapatinib)
(pdb code 8zbu). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of Nanodisc-Reconstituted Human MRP4 WITHE1202Q Mutation (in Complex with Lapatinib), PDB code: 8zbu: Chlorine binding site 1 out of 1 in 8zbuGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Cryo-Em Structure of Nanodisc-Reconstituted Human MRP4 WITHE1202Q Mutation (in Complex with Lapatinib)
![]() Mono view ![]() Stereo pair view
Reference:
Z.Xie,
J.Lv,
W.Huang,
Z.Wu,
R.Zhu,
Z.Deng,
F.Long.
Structural Basis For the Reversal of Human MRP4-Mediated Multidrug Resistance By Lapatinib. Cell Rep V. 44 15466 2025.
Page generated: Sun Jul 13 15:51:16 2025
ISSN: ESSN 2211-1247 PubMed: 40138312 DOI: 10.1016/J.CELREP.2025.115466 |
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