Chlorine in PDB 8zm7: Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction

All present enzymatic activity of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction:
2.6.1.42;

The structure of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction, PDB code: 8zm7 was solved by J.Huang, N.Li, T.Cai, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.69 / 2.30
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	169.904, 169.904, 245.079, 90, 90, 120
R / Rfree (%)	17.2 / 20.5

The structure of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction also contains other interesting chemical elements:

Sodium

(Na)

1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 26;

Binding sites:

The binding sites of Chlorine atom in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction (pdb code 8zm7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 26 binding sites of Chlorine where determined in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction, PDB code: 8zm7:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Chlorine binding site 1 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:65.6 occ:1.00 NH2 A:ARG69 3.4 35.1 1.0 NH1 A:ARG69 3.5 36.7 1.0 CZ A:ARG69 4.0 35.7 1.0 CB A:PRO314 4.0 36.8 1.0 CA A:PRO314 4.6 30.4 1.0 CG A:PRO314 4.8 42.0 1.0 O A:SER317 5.0 31.7 1.0 N A:GLU319 5.0 28.1 1.0

Chlorine binding site 2 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:79.1 occ:1.00 OE1 A:GLU319 4.5 44.0 1.0 CD A:GLU319 4.5 40.0 1.0 OE2 A:GLU319 4.5 57.8 1.0 CB A:ASP321 4.6 39.3 1.0 OD1 A:ASP321 4.9 42.6 1.0 CG A:ASP321 4.9 45.2 1.0 CA A:ASP321 5.0 33.2 1.0

Chlorine binding site 3 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:81.4 occ:1.00 NH1 A:ARG256 3.5 50.5 1.0 NH2 A:ARG256 3.7 57.7 1.0 CZ A:ARG256 4.1 54.9 1.0

Chlorine binding site 4 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl405 b:85.5 occ:1.00 OE1 A:GLN12 4.2 51.9 1.0 CD A:GLN12 4.5 69.6 1.0 CG A:GLN12 4.6 44.8 1.0 CB A:GLN12 4.7 40.8 1.0

Chlorine binding site 5 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl406 b:84.9 occ:1.00 O A:HOH755 3.8 36.8 1.0 OH A:TYR229 4.2 39.5 1.0 CD1 A:LEU264 4.5 32.8 1.0 CZ A:TYR229 4.6 33.5 1.0 CE2 A:TYR229 4.6 32.6 1.0 CD2 A:LEU264 4.9 28.1 1.0

Chlorine binding site 6 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl407 b:73.2 occ:1.00 O A:HOH633 2.8 41.9 1.0 O A:HOH666 3.1 33.6 1.0 O A:HOH690 3.8 30.3 1.0 CA A:GLY217 3.9 28.3 1.0 O A:HOH570 4.0 30.7 1.0 N A:GLY217 4.2 28.6 1.0 CZ2 A:TRP185 4.4 28.0 1.0 CD1 A:LEU188 4.5 26.8 1.0 C A:GLY217 4.5 34.8 1.0 O A:HOH538 4.5 24.6 1.0 OE1 A:GLU214 4.5 30.1 1.0 OE2 A:GLU214 4.6 28.4 1.0 N A:PHE218 4.6 26.3 1.0 CD A:GLU214 4.6 31.1 1.0 CD2 A:LEU236 4.7 30.1 1.0 NZ A:LYS181 4.7 43.6 1.0 NE1 A:TRP185 4.8 25.9 1.0 CB A:LEU236 4.8 28.4 1.0 CE2 A:TRP185 4.8 26.1 1.0 O A:GLY215 4.8 24.8 1.0 O A:HOH625 5.0 29.6 1.0

Chlorine binding site 7 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl401 b:73.5 occ:1.00 O B:HOH636 3.5 32.4 1.0 OD2 B:ASP67 3.6 35.3 1.0 NH1 B:ARG14 3.8 35.0 1.0 O B:HOH590 4.0 36.6 1.0 OH B:TYR312 4.2 38.9 1.0 O B:HOH522 4.4 36.7 1.0 CA B:GLY10 4.4 32.5 1.0 CG B:ASP67 4.6 32.8 1.0

Chlorine binding site 8 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl402 b:87.3 occ:1.00 O1 B:SO4407 3.1 68.8 1.0 O A:HOH681 3.4 44.3 1.0 O B:HOH641 3.4 33.6 1.0 NE B:ARG128 3.9 50.3 1.0 O3 A:GOL412 4.0 65.1 1.0 NE2 B:HIS55 4.3 34.3 1.0 CD B:ARG128 4.4 41.9 1.0 O1 A:GOL412 4.4 63.0 1.0 CH2 A:TRP185 4.4 32.5 1.0 CE1 B:HIS55 4.4 34.2 1.0 S B:SO4407 4.5 62.0 1.0 O A:HOH703 4.8 48.8 1.0 CE2 A:PHE115 4.8 32.3 1.0 CZ B:ARG128 4.8 47.4 1.0 O3 B:SO4407 4.9 61.6 1.0 C3 A:GOL412 4.9 68.4 1.0

Chlorine binding site 9 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:70.9 occ:1.00 NH1 C:ARG69 3.0 29.7 1.0 OE1 C:GLU319 3.4 62.6 1.0 CD C:ARG69 3.4 31.5 1.0 CG C:ARG69 3.5 31.7 1.0 CD C:GLU319 3.8 59.9 1.0 CG C:GLU319 3.8 43.2 1.0 CZ C:ARG69 4.0 29.1 1.0 CB C:GLU319 4.1 38.3 1.0 O C:HOH635 4.2 52.3 1.0 NE C:ARG69 4.2 33.0 1.0 O C:ASP67 4.5 34.3 1.0 OE2 C:GLU319 4.7 84.2 1.0 O C:HOH654 4.8 52.7 1.0 CA C:GLU319 4.9 37.4 1.0

Chlorine binding site 10 out of 26 in the Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 10 of Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl402 b:75.6 occ:1.00 O A:HOH766 3.1 55.4 1.0 CG2 A:VAL259 3.6 32.2 1.0 O C:HOH577 3.7 25.8 1.0 O C:HOH701 3.8 44.9 1.0 CB C:ARG233 4.0 32.1 1.0 CG1 A:VAL259 4.1 29.7 1.0 CG C:PRO173 4.2 31.1 1.0 CB A:VAL259 4.2 33.1 1.0 O C:HOH585 4.3 30.7 1.0 CB C:PRO173 4.4 27.3 1.0 CD C:ARG233 4.6 50.9 1.0 CG C:ARG233 4.7 40.1 1.0 O A:HOH571 4.9 37.6 1.0 ND2 A:ASN211 4.9 24.5 1.0

J.Huang, N.Li, T.Cai. Engineering Omega-Amine Transaminase For Extending Substrate Scope By Ancestral Sequence Reconstruction To Be Published.