Chlorine in PDB 9c6w: Crystal Structure of A Single Chain Trimer Composed of Hla-B*39:06 Y84C Variant, Beta-2MICROGLOBULIN, and Nrvmlpkaa Peptide From NLRP2 (2 Molecules/Asymmetric Unit)

The structure of Crystal Structure of A Single Chain Trimer Composed of Hla-B*39:06 Y84C Variant, Beta-2MICROGLOBULIN, and Nrvmlpkaa Peptide From NLRP2 (2 Molecules/Asymmetric Unit), PDB code: 9c6w was solved by R.Sharma, N.P.Amdare, A.Celikgil, S.J.Garforth, T.P.Dilorenzo, S.C.Almo, A.Ghosh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.73 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	75.244, 84.237, 149.204, 90, 90, 90
R / Rfree (%)	18.7 / 21.6

The binding sites of Chlorine atom in the Crystal Structure of A Single Chain Trimer Composed of Hla-B*39:06 Y84C Variant, Beta-2MICROGLOBULIN, and Nrvmlpkaa Peptide From NLRP2 (2 Molecules/Asymmetric Unit) (pdb code 9c6w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of A Single Chain Trimer Composed of Hla-B*39:06 Y84C Variant, Beta-2MICROGLOBULIN, and Nrvmlpkaa Peptide From NLRP2 (2 Molecules/Asymmetric Unit), PDB code: 9c6w:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of A Single Chain Trimer Composed of Hla-B*39:06 Y84C Variant, Beta-2MICROGLOBULIN, and Nrvmlpkaa Peptide From NLRP2 (2 Molecules/Asymmetric Unit)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of A Single Chain Trimer Composed of Hla-B*39:06 Y84C Variant, Beta-2MICROGLOBULIN, and Nrvmlpkaa Peptide From NLRP2 (2 Molecules/Asymmetric Unit) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl2309 b:68.2 occ:1.00 N A:SER1089 3.2 41.9 1.0 CB B:SER2088 3.3 47.0 1.0 OG B:SER2088 3.4 53.1 1.0 O A:HOH2413 3.5 42.5 1.0 CA A:LEU1088 3.9 31.7 1.0 CB A:SER1089 4.0 51.1 1.0 C A:LEU1088 4.0 40.3 1.0 CA A:SER1089 4.1 43.1 1.0 CD2 A:LEU1088 4.2 42.3 1.0 CB A:LEU1088 4.3 37.6 1.0 N A:GLN1090 4.4 39.4 1.0 CB B:ALA2090 4.6 38.8 1.0 O A:GLN1090 4.6 38.3 1.0 O B:HOH2574 4.7 52.6 1.0 C A:SER1089 4.8 42.8 1.0 O A:THR1087 4.8 38.0 1.0 OG A:SER1089 4.8 59.9 1.0 CA B:SER2088 4.8 50.2 1.0 CG A:LEU1088 4.9 36.1 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of A Single Chain Trimer Composed of Hla-B*39:06 Y84C Variant, Beta-2MICROGLOBULIN, and Nrvmlpkaa Peptide From NLRP2 (2 Molecules/Asymmetric Unit)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of A Single Chain Trimer Composed of Hla-B*39:06 Y84C Variant, Beta-2MICROGLOBULIN, and Nrvmlpkaa Peptide From NLRP2 (2 Molecules/Asymmetric Unit) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl2310 b:71.5 occ:1.00 C B:SER2195 3.7 49.3 1.0 O B:SER2195 3.7 52.2 1.0 CA B:SER2195 3.8 49.1 1.0 N B:SER2195 4.0 47.2 1.0 N B:ASP2196 4.3 51.0 1.0 C B:ILE2194 4.3 51.3 1.0 O B:ILE2194 4.5 53.6 1.0 CB B:PRO2193 4.6 56.8 1.0 CA B:ASP2196 4.9 52.8 1.0 O B:PRO2193 4.9 55.9 1.0 C B:PRO2193 4.9 53.7 1.0

R.Sharma, N.P.Amdare, A.Ghosh, J.Schloss, J.Sidney, S.J.Garforth, Y.Lopez, A.Celikgil, A.Sette, S.C.Almo, T.P.Dilorenzo. Structural and Biochemical Analysis of Highly Similar Hla-B Allotypes Differentially Associated with Type 1 Diabetes. J.Biol.Chem. 07702 2024.
ISSN: ESSN 1083-351X
PubMed: 39173948
DOI: 10.1016/J.JBC.2024.107702