Chlorine in PDB 9dyb: Chip-Tpr in Complex with the Phosphorylated HSP70 Tail

All present enzymatic activity of Chip-Tpr in Complex with the Phosphorylated HSP70 Tail:
2.3.2.27; 3.6.1.3;

The structure of Chip-Tpr in Complex with the Phosphorylated HSP70 Tail, PDB code: 9dyb was solved by H.Zhang, J.C.Nix, R.C.Page, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.60 / 1.60
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	37.575, 45.932, 78.149, 90, 90, 90
R / Rfree (%)	18 / 22

The binding sites of Chlorine atom in the Chip-Tpr in Complex with the Phosphorylated HSP70 Tail (pdb code 9dyb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Chip-Tpr in Complex with the Phosphorylated HSP70 Tail, PDB code: 9dyb:

Chlorine binding site 1 out of 1 in the Chip-Tpr in Complex with the Phosphorylated HSP70 Tail


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Chip-Tpr in Complex with the Phosphorylated HSP70 Tail within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:20.6 occ:1.00 NH1 A:ARG55 3.1 25.2 1.0 NH2 A:ARG55 3.2 33.0 1.0 NE A:ARG51 3.2 18.8 1.0 CZ A:ARG55 3.6 31.1 1.0 NH2 A:ARG51 3.8 20.5 1.0 CZ A:ARG51 3.9 19.1 1.0 CG A:ARG51 4.0 12.9 1.0 CD A:ARG51 4.1 12.8 1.0 CB A:ARG51 4.5 11.2 1.0 NE A:ARG55 4.9 29.3 1.0

M.Stewart, C.Paththamperuma, C.Mccann, K.Cottingim, H.Zhang, R.Delvecchio, I.Peng, E.Fennimore, J.C.Nix, M.N.Saeed, K.George, K.Makaroff, M.Colie, E.Paulakonis, M.F.Almeida, A.J.Afolayan, N.G.Brown, R.C.Page, J.C.Schisler. Phosphorylation-State Modulated Binding of HSP70: Structural Insights and Compensatory Protein Engineering. Biorxiv 2025.
ISSN: ISSN 2692-8205
PubMed: 40027613
DOI: 10.1101/2025.02.17.637997