Chlorine in PDB 9fg9: Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State

The binding sites of Chlorine atom in the Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State (pdb code 9fg9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State, PDB code: 9fg9:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:45.0 occ:1.00 N A:ASN189 3.0 40.2 1.0 N A:VAL53 3.3 38.3 1.0 N A:GLN190 3.6 40.2 1.0 CA A:LEU188 3.6 37.7 1.0 CD2 A:TYR191 3.8 39.3 1.0 C A:LEU188 3.8 42.0 1.0 CA A:PRO52 3.8 35.4 1.0 CD2 A:LEU188 3.9 34.4 1.0 CA A:ASN189 4.0 38.1 1.0 CG A:GLN190 4.0 44.1 1.0 CB A:LEU188 4.1 34.4 1.0 C A:PRO52 4.1 37.5 1.0 O A:VAL53 4.1 51.2 1.0 CB A:ASN189 4.1 36.9 1.0 CB A:VAL53 4.2 38.9 1.0 CA A:VAL53 4.2 37.6 1.0 C A:ASN189 4.3 40.5 1.0 CB A:PRO52 4.3 32.4 1.0 CE2 A:TYR191 4.4 42.0 1.0 N A:TYR191 4.5 39.1 1.0 CG2 A:VAL53 4.6 38.1 1.0 ND2 A:ASN189 4.6 46.5 1.0 O A:ARG187 4.6 40.4 1.0 CA A:GLN190 4.6 40.8 1.0 C A:VAL53 4.7 43.2 1.0 CG A:LEU188 4.7 33.6 1.0 CG A:ASN189 4.7 45.2 1.0 N A:LEU188 4.8 38.8 1.0 CG A:TYR191 4.8 37.4 1.0 C A:GLN190 4.8 41.1 1.0 NE2 A:GLN190 4.8 57.9 1.0 CB A:TYR191 4.9 36.3 1.0 CB A:GLN190 4.9 40.9 1.0

Chlorine binding site 2 out of 3 in the Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl501 b:64.5 occ:1.00 N C:VAL65 3.3 42.2 1.0 N C:TYR199 3.3 51.0 1.0 N C:GLN200 3.6 50.2 1.0 CA C:PRO64 3.8 42.2 1.0 CA C:LEU198 4.0 45.3 1.0 C C:LEU198 4.1 50.2 1.0 C C:PRO64 4.1 43.0 1.0 O C:ARG197 4.1 55.8 1.0 CB C:TYR199 4.1 49.9 1.0 CA C:TYR199 4.1 51.0 1.0 O C:VAL65 4.2 49.9 1.0 CD2 C:PHE201 4.2 43.3 1.0 CB C:VAL65 4.2 38.3 1.0 CA C:VAL65 4.2 39.3 1.0 CB C:PRO64 4.3 43.0 1.0 C C:TYR199 4.4 50.8 1.0 CB C:GLN200 4.5 50.1 1.0 CD2 C:TYR199 4.5 56.6 1.0 CA C:GLN200 4.5 51.9 1.0 CG C:TYR199 4.6 54.4 1.0 CG2 C:VAL65 4.6 39.8 1.0 OE1 C:GLN200 4.6 73.3 1.0 CD2 C:LEU198 4.6 42.3 1.0 CG C:GLN200 4.7 57.8 1.0 C C:VAL65 4.7 42.7 1.0 N C:PHE201 4.7 46.8 1.0 CE2 C:PHE201 4.8 42.9 1.0 C C:ARG197 4.9 50.2 1.0 O C:GLY63 4.9 46.8 1.0 N C:LEU198 5.0 50.0 1.0 CB C:LEU198 5.0 40.7 1.0

Chlorine binding site 3 out of 3 in the Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl501 b:50.4 occ:1.00 N D:ASN189 3.0 41.8 1.0 N D:VAL53 3.4 40.1 1.0 N D:GLN190 3.5 43.9 1.0 CA D:LEU188 3.7 38.7 1.0 CD2 D:TYR191 3.7 41.9 1.0 CD2 D:LEU188 3.8 36.0 1.0 C D:LEU188 3.9 43.4 1.0 CA D:PRO52 3.9 39.2 1.0 CA D:ASN189 4.0 41.5 1.0 CG D:GLN190 4.0 48.7 1.0 CB D:LEU188 4.1 37.1 1.0 O D:VAL53 4.2 57.4 1.0 CB D:ASN189 4.2 41.1 1.0 C D:PRO52 4.2 41.2 1.0 C D:ASN189 4.2 46.7 1.0 CB D:VAL53 4.3 40.4 1.0 CA D:VAL53 4.3 37.9 1.0 CE2 D:TYR191 4.4 44.4 1.0 CB D:PRO52 4.4 38.0 1.0 N D:TYR191 4.4 40.5 1.0 CA D:GLN190 4.5 41.8 1.0 CG D:LEU188 4.6 35.5 1.0 CG2 D:VAL53 4.7 38.2 1.0 CG D:TYR191 4.7 38.4 1.0 C D:GLN190 4.7 42.2 1.0 CB D:TYR191 4.7 34.5 1.0 C D:VAL53 4.7 44.1 1.0 O D:ARG187 4.7 38.6 1.0 ND2 D:ASN189 4.8 50.7 1.0 CG D:ASN189 4.8 51.2 1.0 CB D:GLN190 4.9 42.1 1.0 N D:LEU188 4.9 36.0 1.0

D.B.Mihaylov, T.Malinauskas, A.R.Aricescu. Cryo-Em Structure of the Full-Length ALPHA1BETA3GAMMA2 Gaba(A) Receptor in Complex with Gaba and Etomidate in the Long-Lived Symmetric Desensitised State To Be Published.