Chlorine in PDB 9utb: The Full-Length Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State

The binding sites of Chlorine atom in the The Full-Length Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State (pdb code 9utb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the The Full-Length Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State, PDB code: 9utb:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the The Full-Length Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Full-Length Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1 b:75.8 occ:1.00 CL6 C:RRY1 0.0 75.8 1.0 C6 C:RRY1 1.8 75.8 1.0 C5 C:RRY1 2.7 75.8 1.0 C4 C:RRY1 3.1 75.8 1.0 O6 C:RRJ2 3.1 75.8 1.0 O4 C:RRY1 3.2 75.8 1.0 CD1 A:TYR103 3.6 75.6 1.0 OD2 A:ASP142 3.6 66.7 1.0 CE A:LYS65 3.7 79.4 1.0 CD A:LYS65 3.7 79.4 1.0 CE1 A:TYR103 3.8 75.6 1.0 OG A:SER40 4.0 69.6 1.0 O5 C:RRY1 4.0 75.8 1.0 C6 C:RRJ2 4.4 75.8 1.0 CG A:ASP142 4.5 66.7 1.0 C3 C:RRY1 4.5 75.8 1.0 NZ A:LYS65 4.6 79.4 1.0 O5 C:RRJ2 4.6 75.8 1.0 CB A:SER40 4.6 69.6 1.0 C5 C:RRJ2 4.6 75.8 1.0 CB A:ALA43 4.7 85.1 1.0 C2 C:RRY1 4.7 75.8 1.0 OD1 A:ASP142 4.8 66.7 1.0 CG A:TYR103 4.8 75.6 1.0 O2 C:RRY1 4.8 75.8 1.0

Chlorine binding site 2 out of 3 in the The Full-Length Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Full-Length Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1 b:75.8 occ:1.00 CL1 C:RRY1 0.0 75.8 1.0 C1 C:RRY1 1.8 75.8 1.0 C2 C:RRY1 2.8 75.8 1.0 O5 C:RRY1 3.1 75.8 1.0 C3 C:RRY1 3.2 75.8 1.0 CE2 A:TYR215 3.5 66.8 1.0 OE1 A:GLU302 3.6 67.2 1.0 CD2 A:TYR215 3.7 66.8 1.0 OG A:SER303 3.9 70.7 1.0 O3 C:RRY1 4.0 75.8 1.0 O2 C:RRY1 4.0 75.8 1.0 CB A:SER303 4.0 70.7 1.0 C5 C:RRY1 4.1 75.8 1.0 CZ A:TYR215 4.2 66.8 1.0 CD A:GLU302 4.3 67.2 1.0 C4 C:RRY1 4.4 75.8 1.0 OE2 A:GLU302 4.4 67.2 1.0 CA A:SER303 4.5 70.7 1.0 CG A:TYR215 4.5 66.8 1.0 OH A:TYR215 4.7 66.8 1.0 C1 C:RRJ2 4.7 75.8 1.0 O2 C:RRJ2 4.9 75.8 1.0 CE1 A:TYR215 4.9 66.8 1.0

Chlorine binding site 3 out of 3 in the The Full-Length Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Full-Length Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl2 b:75.8 occ:1.00 CL4 C:RRJ2 0.0 75.8 1.0 C4 C:RRJ2 1.8 75.8 1.0 C3 C:RRJ2 2.7 75.8 1.0 C5 C:RRJ2 2.8 75.8 1.0 O3 C:RRJ2 3.0 75.8 1.0 C6 C:RRJ2 3.1 75.8 1.0 O5 C:RRJ2 3.2 75.8 1.0 C2 C:RRJ2 3.3 75.8 1.0 CG2 A:VAL384 3.6 66.1 1.0 CG2 A:ILE67 3.6 76.7 1.0 CG1 A:VAL384 3.6 66.1 1.0 CB A:VAL384 3.7 66.1 1.0 CD1 A:LEU71 3.8 68.4 1.0 C1 C:RRJ2 3.9 75.8 1.0 CD2 A:LEU71 4.4 68.4 1.0 CB A:SER165 4.5 63.9 1.0 O2 C:RRJ2 4.5 75.8 1.0 CE1 A:TYR164 4.5 60.8 1.0 O6 C:RRJ2 4.5 75.8 1.0 CG A:LEU71 4.6 68.4 1.0 OG A:SER165 4.7 63.9 1.0 CB A:ILE67 4.8 76.7 1.0 O2 C:RRY1 4.8 75.8 1.0 OE2 A:GLU382 4.9 78.7 1.0

Z.Shi, W.Xu, L.Wu, X.Yue, S.Liu, W.Ding, J.Zhang, B.Meng, L.Zhao, X.Liu, J.Liu, Z.J.Liu, T.Hua. Structural and Functional Characterization of Human Sweet Taste Receptor. Nature 2025.
ISSN: ESSN 1476-4687
PubMed: 40555359
DOI: 10.1038/S41586-025-09302-6