Chlorine in PDB 9utc: The Vft Domains of Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State

The binding sites of Chlorine atom in the The Vft Domains of Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State (pdb code 9utc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the The Vft Domains of Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State, PDB code: 9utc:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the The Vft Domains of Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Vft Domains of Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1 b:95.8 occ:1.00 CL6 C:RRY1 0.0 95.8 1.0 C6 C:RRY1 1.8 88.1 1.0 C5 C:RRY1 2.7 88.8 1.0 O4 C:RRY1 3.3 86.0 1.0 C4 C:RRY1 3.3 88.9 1.0 CD1 A:TYR103 3.4 89.7 1.0 OG A:SER40 3.6 78.3 1.0 CG A:TYR103 3.7 89.1 1.0 CD A:LYS65 3.7 82.7 1.0 CE A:LYS65 3.7 84.9 1.0 CE1 A:TYR103 3.9 89.5 1.0 CB A:TYR103 4.0 87.7 1.0 O6 C:RRJ2 4.0 83.0 1.0 O5 C:RRY1 4.0 91.7 1.0 CB A:ALA43 4.0 92.2 1.0 OD2 A:ASP142 4.3 76.9 1.0 CD2 A:TYR103 4.3 88.6 1.0 O A:HIS42 4.4 93.9 1.0 CZ A:TYR103 4.6 90.3 1.0 CA A:TYR103 4.6 87.0 1.0 CB A:SER40 4.6 76.1 1.0 C3 C:RRY1 4.7 89.3 1.0 CG A:LYS65 4.7 84.7 1.0 CE2 A:TYR103 4.8 88.9 1.0 C2 C:RRY1 5.0 91.4 1.0

Chlorine binding site 2 out of 3 in the The Vft Domains of Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Vft Domains of Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1 b:87.9 occ:1.00 CL1 C:RRY1 0.0 87.9 1.0 C1 C:RRY1 1.8 86.5 1.0 C2 C:RRY1 2.8 91.4 1.0 O5 C:RRY1 3.1 91.7 1.0 C3 C:RRY1 3.3 89.3 1.0 OD1 A:ASN143 3.8 80.0 1.0 C5 C:RRY1 4.0 88.8 1.0 O2 C:RRY1 4.0 88.9 1.0 CG A:TYR215 4.1 58.7 1.0 CD1 A:TYR215 4.1 60.7 1.0 O3 C:RRY1 4.1 85.5 1.0 CB A:TYR215 4.2 56.1 1.0 CG A:PRO277 4.3 69.7 1.0 OH A:TYR103 4.3 89.7 1.0 C4 C:RRY1 4.3 88.9 1.0 CD A:PRO277 4.4 69.4 1.0 CD2 A:TYR215 4.6 57.9 1.0 CB A:PRO277 4.6 70.0 1.0 CE1 A:TYR215 4.7 59.5 1.0 CG A:ASN143 4.7 83.1 1.0 C1 C:RRJ2 4.7 84.6 1.0 CB A:SER303 4.8 65.0 1.0 CA A:PRO277 4.8 70.2 1.0 CE1 A:TYR103 4.9 89.5 1.0

Chlorine binding site 3 out of 3 in the The Vft Domains of Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Vft Domains of Human Sweet Taste Receptor TAS1R2 and TAS1R3 in the Sucralose-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl2 b:87.7 occ:1.00 CL4 C:RRJ2 0.0 87.7 1.0 C4 C:RRJ2 1.8 90.1 1.0 C3 C:RRJ2 2.7 88.3 1.0 C5 C:RRJ2 2.8 87.3 1.0 O3 C:RRJ2 3.0 87.0 1.0 OG A:SER165 3.0 65.3 1.0 C6 C:RRJ2 3.1 87.0 1.0 O5 C:RRJ2 3.2 86.9 1.0 C2 C:RRJ2 3.2 84.1 1.0 CD1 A:LEU71 3.6 70.2 1.0 OD1 A:ASP142 3.8 75.0 1.0 C1 C:RRJ2 3.9 84.6 1.0 CB A:SER165 3.9 62.8 1.0 CG2 A:VAL384 4.0 65.0 1.0 CG2 A:ILE67 4.1 83.7 1.0 CB A:VAL384 4.3 62.2 1.0 O2 C:RRJ2 4.5 84.4 1.0 CG1 A:VAL384 4.5 61.5 1.0 O6 C:RRJ2 4.5 83.0 1.0 CG A:LEU71 4.7 67.7 1.0 O2 C:RRY1 4.8 88.9 1.0 CD2 A:LEU71 4.8 71.9 1.0 CG A:ASP142 4.9 75.9 1.0

Z.Shi, W.Xu, L.Wu, X.Yue, S.Liu, W.Ding, J.Zhang, B.Meng, L.Zhao, X.Liu, J.Liu, Z.J.Liu, T.Hua. Structural and Functional Characterization of Human Sweet Taste Receptor. Nature 2025.
ISSN: ESSN 1476-4687
PubMed: 40555359
DOI: 10.1038/S41586-025-09302-6