Atomistry » Chlorine » PDB 1o54-1ome » 1o5w
Atomistry »
  Chlorine »
    PDB 1o54-1ome »
      1o5w »

Chlorine in PDB 1o5w: The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A

Enzymatic activity of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A

All present enzymatic activity of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A:
1.4.3.4;

Protein crystallography data

The structure of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A, PDB code: 1o5w was solved by J.Ma, M.Yoshimura, E.Yamashita, A.Nakagawa, A.Ito, T.Tsukihara, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 16.19 / 3.20
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 157.560, 157.560, 257.840, 90.00, 90.00, 90.00
R / Rfree (%) 22 / 28.2

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A (pdb code 1o5w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A, PDB code: 1o5w:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Chlorine binding site 1 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 1 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl709

b:91.3
occ:1.00
 CL08 A:MLG709 0.0 91.3 1.0
C04 A:MLG709 1.7 48.1 1.0
C03 A:MLG709 2.7 81.3 1.0
C05 A:MLG709 2.8 95.7 1.0
SG A:CYS323 3.0 95.9 1.0
CD1 A:ILE325 3.8 98.8 1.0
C06 A:MLG709 4.1 98.9 1.0
CD1 A:LEU97 4.1 41.4 1.0
C02 A:MLG709 4.1 1.0 1.0
CG1 A:ILE325 4.1 78.9 1.0
CE1 A:PHE208 4.2 58.4 1.0
CZ A:PHE208 4.6 79.7 1.0
C01 A:MLG709 4.6 48.3 1.0
CB A:CYS323 4.6 62.7 1.0
O A:ALA111 4.7 52.8 1.0
CD1 A:PHE208 5.0 78.0 1.0

Chlorine binding site 2 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 2 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl709

b:87.7
occ:1.00
 CL07 A:MLG709 0.0 87.7 1.0
C02 A:MLG709 1.8 1.0 1.0
C03 A:MLG709 2.8 81.3 1.0
C01 A:MLG709 2.8 48.3 1.0
O A:THR336 3.1 40.6 1.0
O09 A:MLG709 3.1 54.4 1.0
CB A:ILE335 3.2 41.3 1.0
N A:THR336 3.3 48.3 1.0
C A:THR336 3.4 63.8 1.0
CG A:LEU337 3.5 89.4 1.0
CD1 A:ILE335 3.5 87.5 1.0
C A:ILE335 3.6 48.0 1.0
CG1 A:ILE335 3.7 89.4 1.0
CA A:THR336 3.7 89.4 1.0
CA A:ILE335 4.0 45.8 1.0
C04 A:MLG709 4.1 48.1 1.0
CD2 A:LEU337 4.1 91.2 1.0
O A:ILE335 4.1 56.1 1.0
CD1 A:LEU337 4.1 35.1 1.0
C06 A:MLG709 4.1 98.9 1.0
CG2 A:ILE335 4.2 66.4 1.0
N A:LEU337 4.3 83.8 1.0
C10 A:MLG709 4.3 50.8 1.0
CB A:LEU337 4.5 51.5 1.0
C05 A:MLG709 4.6 95.7 1.0
CE A:MET350 4.7 95.5 1.0
CA A:LEU337 4.8 61.4 1.0

Chlorine binding site 3 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 3 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1709

b:0.5
occ:1.00
 CL08 B:MLG1709 0.0 0.5 1.0
C04 B:MLG1709 1.8 0.0 1.0
C03 B:MLG1709 2.8 0.8 1.0
C05 B:MLG1709 2.8 0.7 1.0
SG B:CYS1323 3.5 0.6 1.0
CD1 B:ILE1325 3.6 54.7 1.0
CE1 B:PHE1208 3.7 0.9 1.0
CG1 B:ILE1325 4.0 0.2 1.0
CZ B:PHE1208 4.1 0.3 1.0
C06 B:MLG1709 4.1 0.1 1.0
C02 B:MLG1709 4.1 0.1 1.0
CD1 B:LEU1097 4.4 0.7 1.0
O B:ALA1111 4.4 1.0 1.0
CD1 B:PHE1208 4.5 1.0 1.0
C01 B:MLG1709 4.6 0.4 1.0

Chlorine binding site 4 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 4 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1709

b:0.5
occ:1.00
 CL07 B:MLG1709 0.0 0.5 1.0
C02 B:MLG1709 1.8 0.1 1.0
C03 B:MLG1709 2.7 0.8 1.0
C01 B:MLG1709 2.8 0.4 1.0
O09 B:MLG1709 3.1 0.6 1.0
O B:THR1336 3.3 87.2 1.0
CB B:ILE1335 3.3 66.2 1.0
CG B:LEU1337 3.5 0.7 1.0
N B:THR1336 3.6 88.7 1.0
CD1 B:ILE1335 3.6 0.4 1.0
C B:THR1336 3.7 0.7 1.0
CG1 B:ILE1335 3.7 0.6 1.0
C B:ILE1335 3.8 93.0 1.0
CA B:THR1336 4.0 84.2 1.0
CD1 B:LEU1337 4.1 0.8 1.0
CD2 B:LEU1337 4.1 54.0 1.0
C04 B:MLG1709 4.1 0.0 1.0
C06 B:MLG1709 4.1 0.1 1.0
CA B:ILE1335 4.2 75.3 1.0
CG2 B:ILE1335 4.2 65.5 1.0
C10 B:MLG1709 4.3 0.3 1.0
O B:ILE1335 4.3 85.3 1.0
N B:LEU1337 4.5 0.9 1.0
CB B:LEU1337 4.5 84.3 1.0
C05 B:MLG1709 4.6 0.7 1.0
CE B:MET1350 4.7 68.6 1.0
CA B:LEU1337 5.0 0.3 1.0

Chlorine binding site 5 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 5 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl2709

b:0.4
occ:1.00
 CL08 C:MLG2709 0.0 0.4 1.0
C04 C:MLG2709 1.8 0.7 1.0
C03 C:MLG2709 2.8 0.3 1.0
C05 C:MLG2709 2.8 0.7 1.0
SG C:CYS2323 3.2 89.8 1.0
CD1 C:ILE2325 3.5 0.3 1.0
CG1 C:ILE2325 3.8 38.9 1.0
CE1 C:PHE2208 3.9 90.0 1.0
C06 C:MLG2709 4.1 0.7 1.0
C02 C:MLG2709 4.1 0.4 1.0
CZ C:PHE2208 4.3 97.1 1.0
CD1 C:LEU2097 4.3 89.4 1.0
C01 C:MLG2709 4.6 76.6 1.0
O C:ALA2111 4.7 94.5 1.0
CD1 C:PHE2208 4.8 43.3 1.0
CB C:CYS2323 4.9 71.7 1.0

Chlorine binding site 6 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 6 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl2709

b:62.6
occ:1.00
 CL07 C:MLG2709 0.0 62.6 1.0
C02 C:MLG2709 1.8 0.4 1.0
C03 C:MLG2709 2.8 0.3 1.0
C01 C:MLG2709 2.8 76.6 1.0
CB C:ILE2335 3.1 89.4 1.0
O09 C:MLG2709 3.1 77.1 1.0
O C:THR2336 3.2 40.9 1.0
N C:THR2336 3.3 34.4 1.0
CD1 C:ILE2335 3.4 85.0 1.0
C C:THR2336 3.5 42.0 1.0
CG1 C:ILE2335 3.5 53.0 1.0
C C:ILE2335 3.5 42.8 1.0
CG C:LEU2337 3.6 56.7 1.0
CA C:THR2336 3.7 45.0 1.0
CA C:ILE2335 3.9 63.1 1.0
O C:ILE2335 4.0 49.5 1.0
CG2 C:ILE2335 4.1 65.9 1.0
C04 C:MLG2709 4.1 0.7 1.0
C06 C:MLG2709 4.1 0.7 1.0
CD1 C:LEU2337 4.2 47.8 1.0
CD2 C:LEU2337 4.2 74.8 1.0
N C:LEU2337 4.3 81.5 1.0
C10 C:MLG2709 4.3 86.5 1.0
CB C:LEU2337 4.6 89.4 1.0
C05 C:MLG2709 4.7 0.7 1.0
CE C:MET2350 4.7 0.2 1.0
CA C:LEU2337 4.9 48.9 1.0

Chlorine binding site 7 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 7 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl3709

b:0.5
occ:1.00
 CL08 D:MLG3709 0.0 0.5 1.0
C04 D:MLG3709 1.8 0.7 1.0
C03 D:MLG3709 2.8 0.5 1.0
C05 D:MLG3709 2.8 0.5 1.0
SG D:CYS3323 3.4 0.1 1.0
CD1 D:ILE3325 3.7 87.8 1.0
CE1 D:PHE3208 3.7 0.5 1.0
CG1 D:ILE3325 4.1 92.9 1.0
C06 D:MLG3709 4.1 0.2 1.0
C02 D:MLG3709 4.1 0.2 1.0
CZ D:PHE3208 4.1 0.2 1.0
CD1 D:LEU3097 4.3 85.3 1.0
O D:ALA3111 4.4 64.8 1.0
CD1 D:PHE3208 4.6 0.8 1.0
C01 D:MLG3709 4.6 0.9 1.0

Chlorine binding site 8 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 8 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl3709

b:1.0
occ:1.00
 CL07 D:MLG3709 0.0 1.0 1.0
C02 D:MLG3709 1.8 0.2 1.0
C03 D:MLG3709 2.8 0.5 1.0
C01 D:MLG3709 2.8 0.9 1.0
O09 D:MLG3709 3.1 0.9 1.0
CB D:ILE3335 3.2 44.6 1.0
O D:THR3336 3.3 68.8 1.0
N D:THR3336 3.4 87.5 1.0
CD1 D:ILE3335 3.5 1.0 1.0
CG1 D:ILE3335 3.6 0.7 1.0
CG D:LEU3337 3.6 0.7 1.0
C D:THR3336 3.6 99.8 1.0
C D:ILE3335 3.7 68.2 1.0
CA D:THR3336 3.9 89.3 1.0
CA D:ILE3335 4.0 74.5 1.0
CG2 D:ILE3335 4.1 86.4 1.0
C04 D:MLG3709 4.1 0.7 1.0
C06 D:MLG3709 4.1 0.2 1.0
CD2 D:LEU3337 4.2 75.2 1.0
CD1 D:LEU3337 4.2 0.6 1.0
O D:ILE3335 4.2 86.6 1.0
C10 D:MLG3709 4.3 0.8 1.0
N D:LEU3337 4.4 79.8 1.0
CB D:LEU3337 4.6 0.8 1.0
C05 D:MLG3709 4.6 0.5 1.0
CE D:MET3350 4.8 91.5 1.0
CA D:LEU3337 5.0 62.4 1.0

Reference:

J.Ma, M.Yoshimura, E.Yamashita, A.Nakagawa, A.Ito, T.Tsukihara. Structure of Rat Monoamine Oxidase A and Its Specific Recognitions For Substrates and Inhibitors. J.Mol.Biol. V. 338 103 2004.
ISSN: ISSN 0022-2836
PubMed: 15050826
DOI: 10.1016/J.JMB.2004.02.032
Page generated: Sat Dec 12 08:44:39 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy