Atomistry » Chlorine » PDB 1o5e-1omy » 1o5w
Atomistry »
  Chlorine »
    PDB 1o5e-1omy »
      1o5w »

Chlorine in PDB 1o5w: The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A

Enzymatic activity of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A

All present enzymatic activity of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A:
1.4.3.4;

Protein crystallography data

The structure of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A, PDB code: 1o5w was solved by J.Ma, M.Yoshimura, E.Yamashita, A.Nakagawa, A.Ito, T.Tsukihara, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 16.19 / 3.20
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 157.560, 157.560, 257.840, 90.00, 90.00, 90.00
R / Rfree (%) 22 / 28.2

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A (pdb code 1o5w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A, PDB code: 1o5w:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Chlorine binding site 1 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 1 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl709

b:91.3
occ:1.00
 CL08 A:MLG709 0.0 91.3 1.0
C04 A:MLG709 1.7 48.1 1.0
C03 A:MLG709 2.7 81.3 1.0
C05 A:MLG709 2.8 95.7 1.0
SG A:CYS323 3.0 95.9 1.0
CD1 A:ILE325 3.8 98.8 1.0
C06 A:MLG709 4.1 98.9 1.0
CD1 A:LEU97 4.1 41.4 1.0
C02 A:MLG709 4.1 1.0 1.0
CG1 A:ILE325 4.1 78.9 1.0
CE1 A:PHE208 4.2 58.4 1.0
CZ A:PHE208 4.6 79.7 1.0
C01 A:MLG709 4.6 48.3 1.0
CB A:CYS323 4.6 62.7 1.0
O A:ALA111 4.7 52.8 1.0
CD1 A:PHE208 5.0 78.0 1.0

Chlorine binding site 2 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 2 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl709

b:87.7
occ:1.00
 CL07 A:MLG709 0.0 87.7 1.0
C02 A:MLG709 1.8 1.0 1.0
C03 A:MLG709 2.8 81.3 1.0
C01 A:MLG709 2.8 48.3 1.0
O A:THR336 3.1 40.6 1.0
O09 A:MLG709 3.1 54.4 1.0
CB A:ILE335 3.2 41.3 1.0
N A:THR336 3.3 48.3 1.0
C A:THR336 3.4 63.8 1.0
CG A:LEU337 3.5 89.4 1.0
CD1 A:ILE335 3.5 87.5 1.0
C A:ILE335 3.6 48.0 1.0
CG1 A:ILE335 3.7 89.4 1.0
CA A:THR336 3.7 89.4 1.0
CA A:ILE335 4.0 45.8 1.0
C04 A:MLG709 4.1 48.1 1.0
CD2 A:LEU337 4.1 91.2 1.0
O A:ILE335 4.1 56.1 1.0
CD1 A:LEU337 4.1 35.1 1.0
C06 A:MLG709 4.1 98.9 1.0
CG2 A:ILE335 4.2 66.4 1.0
N A:LEU337 4.3 83.8 1.0
C10 A:MLG709 4.3 50.8 1.0
CB A:LEU337 4.5 51.5 1.0
C05 A:MLG709 4.6 95.7 1.0
CE A:MET350 4.7 95.5 1.0
CA A:LEU337 4.8 61.4 1.0

Chlorine binding site 3 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 3 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1709

b:0.5
occ:1.00
 CL08 B:MLG1709 0.0 0.5 1.0
C04 B:MLG1709 1.8 0.0 1.0
C03 B:MLG1709 2.8 0.8 1.0
C05 B:MLG1709 2.8 0.7 1.0
SG B:CYS1323 3.5 0.6 1.0
CD1 B:ILE1325 3.6 54.7 1.0
CE1 B:PHE1208 3.7 0.9 1.0
CG1 B:ILE1325 4.0 0.2 1.0
CZ B:PHE1208 4.1 0.3 1.0
C06 B:MLG1709 4.1 0.1 1.0
C02 B:MLG1709 4.1 0.1 1.0
CD1 B:LEU1097 4.4 0.7 1.0
O B:ALA1111 4.4 1.0 1.0
CD1 B:PHE1208 4.5 1.0 1.0
C01 B:MLG1709 4.6 0.4 1.0

Chlorine binding site 4 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 4 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1709

b:0.5
occ:1.00
 CL07 B:MLG1709 0.0 0.5 1.0
C02 B:MLG1709 1.8 0.1 1.0
C03 B:MLG1709 2.7 0.8 1.0
C01 B:MLG1709 2.8 0.4 1.0
O09 B:MLG1709 3.1 0.6 1.0
O B:THR1336 3.3 87.2 1.0
CB B:ILE1335 3.3 66.2 1.0
CG B:LEU1337 3.5 0.7 1.0
N B:THR1336 3.6 88.7 1.0
CD1 B:ILE1335 3.6 0.4 1.0
C B:THR1336 3.7 0.7 1.0
CG1 B:ILE1335 3.7 0.6 1.0
C B:ILE1335 3.8 93.0 1.0
CA B:THR1336 4.0 84.2 1.0
CD1 B:LEU1337 4.1 0.8 1.0
CD2 B:LEU1337 4.1 54.0 1.0
C04 B:MLG1709 4.1 0.0 1.0
C06 B:MLG1709 4.1 0.1 1.0
CA B:ILE1335 4.2 75.3 1.0
CG2 B:ILE1335 4.2 65.5 1.0
C10 B:MLG1709 4.3 0.3 1.0
O B:ILE1335 4.3 85.3 1.0
N B:LEU1337 4.5 0.9 1.0
CB B:LEU1337 4.5 84.3 1.0
C05 B:MLG1709 4.6 0.7 1.0
CE B:MET1350 4.7 68.6 1.0
CA B:LEU1337 5.0 0.3 1.0

Chlorine binding site 5 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 5 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl2709

b:0.4
occ:1.00
 CL08 C:MLG2709 0.0 0.4 1.0
C04 C:MLG2709 1.8 0.7 1.0
C03 C:MLG2709 2.8 0.3 1.0
C05 C:MLG2709 2.8 0.7 1.0
SG C:CYS2323 3.2 89.8 1.0
CD1 C:ILE2325 3.5 0.3 1.0
CG1 C:ILE2325 3.8 38.9 1.0
CE1 C:PHE2208 3.9 90.0 1.0
C06 C:MLG2709 4.1 0.7 1.0
C02 C:MLG2709 4.1 0.4 1.0
CZ C:PHE2208 4.3 97.1 1.0
CD1 C:LEU2097 4.3 89.4 1.0
C01 C:MLG2709 4.6 76.6 1.0
O C:ALA2111 4.7 94.5 1.0
CD1 C:PHE2208 4.8 43.3 1.0
CB C:CYS2323 4.9 71.7 1.0

Chlorine binding site 6 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 6 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl2709

b:62.6
occ:1.00
 CL07 C:MLG2709 0.0 62.6 1.0
C02 C:MLG2709 1.8 0.4 1.0
C03 C:MLG2709 2.8 0.3 1.0
C01 C:MLG2709 2.8 76.6 1.0
CB C:ILE2335 3.1 89.4 1.0
O09 C:MLG2709 3.1 77.1 1.0
O C:THR2336 3.2 40.9 1.0
N C:THR2336 3.3 34.4 1.0
CD1 C:ILE2335 3.4 85.0 1.0
C C:THR2336 3.5 42.0 1.0
CG1 C:ILE2335 3.5 53.0 1.0
C C:ILE2335 3.5 42.8 1.0
CG C:LEU2337 3.6 56.7 1.0
CA C:THR2336 3.7 45.0 1.0
CA C:ILE2335 3.9 63.1 1.0
O C:ILE2335 4.0 49.5 1.0
CG2 C:ILE2335 4.1 65.9 1.0
C04 C:MLG2709 4.1 0.7 1.0
C06 C:MLG2709 4.1 0.7 1.0
CD1 C:LEU2337 4.2 47.8 1.0
CD2 C:LEU2337 4.2 74.8 1.0
N C:LEU2337 4.3 81.5 1.0
C10 C:MLG2709 4.3 86.5 1.0
CB C:LEU2337 4.6 89.4 1.0
C05 C:MLG2709 4.7 0.7 1.0
CE C:MET2350 4.7 0.2 1.0
CA C:LEU2337 4.9 48.9 1.0

Chlorine binding site 7 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 7 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl3709

b:0.5
occ:1.00
 CL08 D:MLG3709 0.0 0.5 1.0
C04 D:MLG3709 1.8 0.7 1.0
C03 D:MLG3709 2.8 0.5 1.0
C05 D:MLG3709 2.8 0.5 1.0
SG D:CYS3323 3.4 0.1 1.0
CD1 D:ILE3325 3.7 87.8 1.0
CE1 D:PHE3208 3.7 0.5 1.0
CG1 D:ILE3325 4.1 92.9 1.0
C06 D:MLG3709 4.1 0.2 1.0
C02 D:MLG3709 4.1 0.2 1.0
CZ D:PHE3208 4.1 0.2 1.0
CD1 D:LEU3097 4.3 85.3 1.0
O D:ALA3111 4.4 64.8 1.0
CD1 D:PHE3208 4.6 0.8 1.0
C01 D:MLG3709 4.6 0.9 1.0

Chlorine binding site 8 out of 8 in 1o5w

Go back to Chlorine Binding Sites List in 1o5w
Chlorine binding site 8 out of 8 in the The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of The Structure Basis of Specific Recognitions For Substrates and Inhibitors of Rat Monoamine Oxidase A within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl3709

b:1.0
occ:1.00
 CL07 D:MLG3709 0.0 1.0 1.0
C02 D:MLG3709 1.8 0.2 1.0
C03 D:MLG3709 2.8 0.5 1.0
C01 D:MLG3709 2.8 0.9 1.0
O09 D:MLG3709 3.1 0.9 1.0
CB D:ILE3335 3.2 44.6 1.0
O D:THR3336 3.3 68.8 1.0
N D:THR3336 3.4 87.5 1.0
CD1 D:ILE3335 3.5 1.0 1.0
CG1 D:ILE3335 3.6 0.7 1.0
CG D:LEU3337 3.6 0.7 1.0
C D:THR3336 3.6 99.8 1.0
C D:ILE3335 3.7 68.2 1.0
CA D:THR3336 3.9 89.3 1.0
CA D:ILE3335 4.0 74.5 1.0
CG2 D:ILE3335 4.1 86.4 1.0
C04 D:MLG3709 4.1 0.7 1.0
C06 D:MLG3709 4.1 0.2 1.0
CD2 D:LEU3337 4.2 75.2 1.0
CD1 D:LEU3337 4.2 0.6 1.0
O D:ILE3335 4.2 86.6 1.0
C10 D:MLG3709 4.3 0.8 1.0
N D:LEU3337 4.4 79.8 1.0
CB D:LEU3337 4.6 0.8 1.0
C05 D:MLG3709 4.6 0.5 1.0
CE D:MET3350 4.8 91.5 1.0
CA D:LEU3337 5.0 62.4 1.0

Reference:

J.Ma, M.Yoshimura, E.Yamashita, A.Nakagawa, A.Ito, T.Tsukihara. Structure of Rat Monoamine Oxidase A and Its Specific Recognitions For Substrates and Inhibitors. J.Mol.Biol. V. 338 103 2004.
ISSN: ISSN 0022-2836
PubMed: 15050826
DOI: 10.1016/J.JMB.2004.02.032
Page generated: Sat Jul 20 00:48:25 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy