Atomistry » Chlorine » PDB 1p6y-1pqo » 1phb
Atomistry »
  Chlorine »
    PDB 1p6y-1pqo »
      1phb »

Chlorine in PDB 1phb: Inhibitor-Induced Conformational Change in Cytochrome P450-Cam

Enzymatic activity of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam

All present enzymatic activity of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam:
1.14.15.1;

Protein crystallography data

The structure of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam, PDB code: 1phb was solved by T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 1.60
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 108.670, 103.900, 36.380, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Other elements in 1phb:

The structure of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam also contains other interesting chemical elements:

Iron (Fe) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Inhibitor-Induced Conformational Change in Cytochrome P450-Cam (pdb code 1phb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Inhibitor-Induced Conformational Change in Cytochrome P450-Cam, PDB code: 1phb:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 1phb

Go back to Chlorine Binding Sites List in 1phb
Chlorine binding site 1 out of 2 in the Inhibitor-Induced Conformational Change in Cytochrome P450-Cam


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl422

b:28.0
occ:0.20
CL21 A:PFZ422 0.0 28.0 0.2
C16 A:PFZ422 1.7 28.1 1.0
C7 A:PFZ422 2.1 27.9 1.0
C4 A:PFZ422 2.6 27.9 1.0
C8 A:PFZ422 2.6 26.9 1.0
C15 A:PFZ422 2.7 28.1 1.0
C3 A:PFZ422 2.8 27.8 1.0
C6 A:PFZ422 2.8 28.2 1.0
C1 A:PFZ422 3.2 27.6 1.0
CG2 A:THR101 3.5 22.6 1.0
CD1 A:LEU244 3.6 19.9 1.0
C9 A:PFZ422 3.8 27.4 1.0
OG1 A:THR101 3.9 22.6 1.0
C14 A:PFZ422 4.0 28.7 1.0
CB A:THR101 4.0 20.3 1.0
C12 A:PFZ422 4.0 28.2 1.0
O2 A:PFZ422 4.1 27.4 1.0
C17 A:PFZ422 4.1 25.1 1.0
CZ A:PHE87 4.3 21.4 1.0
CE1 A:PHE87 4.4 19.9 1.0
C5 A:PFZ422 4.4 27.2 1.0
N11 A:PFZ422 4.4 25.4 1.0
C10 A:PFZ422 4.5 26.9 1.0
C13 A:PFZ422 4.5 28.2 1.0
OD2 A:ASP297 4.7 16.4 1.0
CBA A:HEM417 4.7 10.1 1.0
O A:HOH712 4.9 20.5 0.9
C18 A:PFZ422 4.9 25.5 1.0
CG A:LEU244 5.0 20.0 1.0
O2A A:HEM417 5.0 11.3 1.0

Chlorine binding site 2 out of 2 in 1phb

Go back to Chlorine Binding Sites List in 1phb
Chlorine binding site 2 out of 2 in the Inhibitor-Induced Conformational Change in Cytochrome P450-Cam


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Inhibitor-Induced Conformational Change in Cytochrome P450-Cam within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl422

b:28.0
occ:0.20
CL22 A:PFZ422 0.0 28.0 0.2
C14 A:PFZ422 1.7 28.7 1.0
C13 A:PFZ422 2.7 28.2 1.0
OD1 A:ASP297 2.7 16.9 1.0
C15 A:PFZ422 2.7 28.1 1.0
CG A:ASP297 2.7 14.0 1.0
OD2 A:ASP297 2.9 16.4 1.0
CG1 A:VAL295 3.0 10.4 1.0
NE2 A:GLN322 3.2 9.7 1.0
CB A:ASP297 3.3 14.6 1.0
OE1 A:GLN322 3.3 10.1 1.0
CBA A:HEM417 3.5 10.1 1.0
N A:ASP297 3.5 12.1 1.0
CD A:GLN322 3.5 8.3 1.0
CA A:ASP297 3.9 12.7 1.0
CMA A:HEM417 3.9 11.1 1.0
C12 A:PFZ422 4.0 28.2 1.0
C16 A:PFZ422 4.0 28.1 1.0
O2A A:HEM417 4.1 11.3 1.0
CGA A:HEM417 4.1 9.7 1.0
C A:ALA296 4.2 10.3 1.0
C3A A:HEM417 4.4 12.2 1.0
CB A:VAL295 4.5 8.9 1.0
C3 A:PFZ422 4.5 27.8 1.0
CAA A:HEM417 4.5 10.8 1.0
N A:ALA296 4.6 8.4 1.0
C2A A:HEM417 4.6 11.4 1.0
CG A:GLN322 4.7 9.9 1.0
CA A:ALA296 4.8 10.2 1.0
C A:ASP297 4.8 12.8 1.0
O A:ALA296 4.9 11.2 1.0
C A:VAL295 4.9 7.2 1.0
OH A:TYR75 5.0 10.2 1.0

Reference:

R.Raag, H.Li, B.C.Jones, T.L.Poulos. Inhibitor-Induced Conformational Change in Cytochrome P-450CAM. Biochemistry V. 32 4571 1993.
ISSN: ISSN 0006-2960
PubMed: 8485133
DOI: 10.1021/BI00068A013
Page generated: Sat Dec 12 08:45:54 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy