Chlorine in PDB 1q86: Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.

The structure of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit., PDB code: 1q86 was solved by J.L.Hansen, T.M.Schmeing, P.B.Moore, T.A.Steitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 3.00
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	213.163, 301.288, 575.397, 90.00, 90.00, 90.00
R / Rfree (%)	23.4 / 26.4

The structure of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. also contains other interesting chemical elements:

Magnesium	(Mg)	118 atoms
Potassium	(K)	2 atoms
Cadmium	(Cd)	5 atoms
Sodium	(Na)	86 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 22;

Binding sites:

The binding sites of Chlorine atom in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. (pdb code 1q86). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 22 binding sites of Chlorine where determined in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit., PDB code: 1q86:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Chlorine binding site 1 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl8503 b:47.6 occ:1.00 N2 A:G1676 3.1 46.6 1.0 O A:HOH8946 3.5 64.4 1.0 O A:HOH5331 3.6 28.6 1.0 C1' A:G1452 3.6 49.9 1.0 O A:HOH7085 3.8 60.7 1.0 CE 3:LYS2 4.0 43.5 1.0 O2' A:G1452 4.0 47.0 1.0 O A:HOH3091 4.0 67.5 1.0 O4' A:G1452 4.2 49.4 1.0 C2 A:G1676 4.2 45.6 1.0 C2 A:A1486 4.3 37.8 1.0 N3 A:A1486 4.4 40.0 1.0 O2 A:C1451 4.4 48.3 1.0 C2' A:G1452 4.4 48.0 1.0 N3 A:G1676 4.4 45.8 1.0 N9 A:G1452 4.5 51.6 1.0 O A:HOH4231 4.6 80.2 1.0 N3 A:G1452 4.7 53.0 1.0 O A:HOH6301 4.7 50.5 1.0 CD 3:LYS2 4.8 40.2 1.0 C4 A:G1452 4.9 52.5 1.0

Chlorine binding site 2 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl8505 b:60.5 occ:1.00 N2 A:G201 3.1 55.2 1.0 O A:HOH4425 3.2 49.4 1.0 O A:HOH4062 3.4 81.3 1.0 O A:HOH9705 3.5 45.5 1.0 C1' A:U202 3.7 53.4 1.0 O4' A:U202 3.7 55.6 1.0 C5 A:C197 3.7 46.4 1.0 C5' A:G229 3.9 52.0 1.0 C2 A:G201 4.1 55.6 1.0 O3' A:G229 4.2 50.0 1.0 C4' A:G229 4.3 52.0 1.0 N3 A:G201 4.3 55.6 1.0 O2' A:U202 4.4 54.0 1.0 N1 A:U202 4.5 53.6 1.0 C6 A:C197 4.5 44.7 1.0 O2 A:U202 4.6 56.5 1.0 N4 A:C197 4.6 46.4 1.0 C4 A:C197 4.7 45.9 1.0 C4' A:U202 4.7 53.3 1.0 O2 A:C195 4.7 42.2 1.0 C2' A:U202 4.7 52.8 1.0 O A:HOH9270 4.7 28.1 1.0 OP1 A:G229 4.8 51.5 1.0 C2 A:U202 4.8 54.8 1.0 N1 A:A199 4.8 64.9 1.0 C3' A:G229 4.8 52.0 1.0 C2 A:A199 4.9 65.2 1.0 OP1 A:C230 4.9 51.8 1.0

Chlorine binding site 3 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl8511 b:65.6 occ:1.00 N R:HIS53 3.0 37.4 1.0 O2' A:C2388 3.1 31.9 1.0 O A:HOH9686 3.3 15.5 1.0 CB R:PHE52 3.7 38.2 1.0 CA R:PHE52 3.7 39.2 1.0 CB R:HIS53 3.8 37.9 1.0 C R:PHE52 3.8 38.9 1.0 CE2 R:PHE56 3.9 32.2 1.0 O4' A:C2388 3.9 31.6 1.0 C4' A:C2388 3.9 31.0 1.0 CD2 R:PHE56 4.0 32.3 1.0 C1' A:C2388 4.0 30.9 1.0 CA R:HIS53 4.0 35.7 1.0 C2' A:C2388 4.1 31.9 1.0 CG2 R:ILE84 4.1 37.0 1.0 O A:HOH3110 4.1 45.0 1.0 O A:HOH3920 4.2 50.5 1.0 C3' A:C2388 4.6 32.5 1.0 CG1 R:ILE84 4.7 37.1 1.0 O A:HOH9670 4.8 37.7 1.0 CB R:ILE84 4.9 37.1 1.0 CD1 R:ILE84 4.9 38.4 1.0 O3' A:C2388 5.0 32.5 1.0 CG R:PHE52 5.0 37.6 1.0

Chlorine binding site 4 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl8513 b:50.1 occ:1.00 O A:HOH4181 2.7 0.3 1.0 N1 A:A1329 2.9 30.9 1.0 O A:HOH4466 3.3 47.2 1.0 O2' A:G1300 3.5 33.3 1.0 N6 A:A1328 3.6 26.4 1.0 C2 A:A1329 3.6 29.1 1.0 O A:HOH3162 3.8 29.2 1.0 N2 A:G1299 3.8 32.0 1.0 C1' A:G1300 3.9 35.3 1.0 C6 A:A1329 3.9 31.5 1.0 O Z:HOH8531 4.0 34.9 1.0 N6 A:A1329 4.0 33.7 1.0 O4' A:G1300 4.1 34.9 1.0 N1 A:A1330 4.3 32.7 1.0 C2' A:G1300 4.4 35.0 1.0 N3 A:G1299 4.5 33.3 1.0 C2 A:G1299 4.6 32.3 1.0 C4' A:G1300 4.6 34.4 1.0 C2 A:A1330 4.8 34.0 1.0 C6 A:A1328 4.9 24.7 1.0 N3 A:A1329 5.0 31.1 1.0

Chlorine binding site 5 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl8514 b:55.5 occ:1.00 O M:HOH8592 3.1 35.0 1.0 ND1 M:HIS13 3.1 25.1 1.0 O2' A:G644 3.3 29.1 1.0 CG M:GLN7 3.7 29.9 1.0 C2' A:G644 3.9 27.2 1.0 CE1 M:HIS13 4.0 24.9 1.0 CG M:HIS13 4.0 25.1 1.0 CG M:LYS4 4.1 28.3 1.0 N9 A:G644 4.1 24.3 1.0 CB M:HIS13 4.2 23.2 1.0 C4 A:G644 4.3 24.1 1.0 O A:HOH9704 4.3 42.6 1.0 C8 A:G644 4.4 26.0 1.0 CB M:GLN7 4.4 26.4 1.0 C1' A:G644 4.5 26.8 1.0 CA M:LYS4 4.6 28.0 1.0 C5 A:G644 4.6 24.8 1.0 N3 A:G644 4.6 24.1 1.0 CD M:GLN7 4.7 33.1 1.0 N7 A:G644 4.7 25.5 1.0 CB M:LYS4 4.8 27.0 1.0 O A:HOH6609 4.8 57.0 1.0 CD M:LYS4 5.0 28.4 1.0

Chlorine binding site 6 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl8515 b:85.4 occ:1.00 N6 A:A1598 3.2 53.7 1.0 N2 A:G1646 3.4 56.4 1.0 N6 A:A1597 3.4 50.9 1.0 O A:HOH6297 3.8 58.1 1.0 N7 A:A1597 4.1 49.6 1.0 C1' A:G1647 4.1 50.7 1.0 C6 A:A1598 4.2 51.5 1.0 O4' A:G1647 4.3 49.5 1.0 C1' A:G1540 4.3 56.6 1.0 C6 A:A1597 4.4 49.7 1.0 C2 A:G1646 4.5 56.7 1.0 C5 A:A1597 4.6 50.1 1.0 N3 A:G1646 4.6 56.6 1.0 N3 A:G1540 4.7 58.0 1.0 O2' A:G1540 4.7 57.2 1.0 O2' A:U1596 4.8 58.5 1.0 O4' A:G1540 4.8 55.2 1.0 C5 A:A1598 4.9 51.5 1.0 N9 A:G1647 4.9 51.6 1.0 O2' A:G1647 4.9 46.4 1.0 N7 A:A1598 4.9 52.8 1.0 N1 A:A1598 5.0 51.3 1.0

Chlorine binding site 7 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl8516 b:51.6 occ:1.00 O2' A:G1119 3.1 31.1 1.0 NZ K:LYS56 3.2 35.1 1.0 C8 A:G1119 3.5 27.8 1.0 N4 A:C1243 3.6 34.8 1.0 CD K:LYS56 3.6 37.1 1.0 C2' A:G1119 3.9 31.9 1.0 CE K:LYS56 3.9 37.4 1.0 OE1 K:GLN52 4.1 42.3 1.0 N7 A:G1119 4.1 27.4 1.0 NE2 K:GLN52 4.1 43.5 1.0 N9 A:G1119 4.2 27.8 1.0 CD K:GLN52 4.5 43.4 1.0 C1' A:G1119 4.5 30.6 1.0 C4 A:C1243 4.6 36.1 1.0 C5 A:C1243 4.7 36.1 1.0 N6 A:A1242 4.7 34.1 1.0 O A:HOH6447 4.8 47.8 1.0 CG K:LYS56 5.0 35.7 1.0

Chlorine binding site 8 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl8517 b:61.6 occ:1.00 O2' A:C594 2.8 44.3 1.0 O Z:HOH8553 2.9 97.4 1.0 O4' A:U595 3.4 53.8 1.0 O Z:HOH8533 3.4 46.4 1.0 C4' A:U595 3.5 51.3 1.0 O Z:HOH8593 3.5 31.1 1.0 C5' A:U595 3.6 47.3 1.0 C2' A:C594 3.7 46.4 1.0 CG Z:ARG115 3.7 47.8 1.0 NH2 Z:ARG122 3.8 45.5 1.0 CD Z:ARG115 3.8 48.6 1.0 NE Z:ARG115 3.9 50.6 1.0 O A:HOH6042 4.5 60.1 1.0 C1' A:U595 4.6 53.9 1.0 O2 A:C594 4.6 50.8 1.0 C1' A:C594 4.7 48.1 1.0 O A:HOH5799 4.7 48.9 1.0 O5' A:U595 4.7 44.6 1.0 CZ Z:ARG122 4.9 45.2 1.0 C3' A:C594 4.9 45.8 1.0 O3' A:C594 4.9 43.4 1.0

Chlorine binding site 9 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl8522 b:78.0 occ:1.00 N1 A:G1072 3.1 26.4 1.0 O A:HOH4847 3.2 72.9 1.0 C8 A:G1087 3.2 30.9 1.0 N2 A:G1072 3.4 21.5 1.0 O2' A:G1087 3.5 34.1 1.0 N7 A:G1087 3.7 30.3 1.0 C2 A:G1072 3.8 25.5 1.0 N9 A:G1087 3.8 30.9 1.0 C2' A:G1087 3.8 32.7 1.0 N7 A:A1291 4.0 37.6 1.0 C6 A:G1072 4.1 26.5 1.0 O6 A:G1072 4.1 26.9 1.0 O A:HOH8666 4.2 32.3 1.0 C5 A:A1291 4.3 37.5 1.0 OE2 X:GLU10 4.3 44.9 1.0 C1' A:G1087 4.4 32.4 1.0 C5 A:G1087 4.4 30.6 1.0 N6 A:A1291 4.5 39.9 1.0 C4 A:G1087 4.5 30.0 1.0 C8 A:A1291 4.5 35.9 1.0 C6 A:A1291 4.6 37.8 1.0

Chlorine binding site 10 out of 22 in the Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 10 of Crystal Structure of Cca-Phe-Cap-Biotin Bound Simultaneously at Half Occupancy to Both the A-Site and P-Site of the the 50S Ribosomal Subunit. within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl8509 b:55.2 occ:1.00 NZ C:LYS178 3.1 41.5 1.0 O A:HOH5912 3.6 30.8 1.0 CE C:LYS178 3.6 41.4 1.0 CE C:LYS175 3.8 33.3 1.0 CD C:LYS178 3.8 40.0 1.0 O A:HOH4747 3.8 41.1 1.0 O C:HOH8572 4.1 44.9 1.0 CZ C:PHE169 4.2 34.6 1.0 CE1 C:PHE169 4.4 36.0 1.0 SD C:MET179 4.6 41.4 1.0 CD C:LYS175 4.7 34.2 1.0 O A:HOH9571 4.8 44.7 1.0 O A:HOH6167 4.8 47.5 1.0 CE C:MET179 4.8 42.0 1.0 OP2 A:G1878 4.8 41.2 1.0 NZ C:LYS175 4.9 31.2 1.0 CG C:LYS178 4.9 38.2 1.0

J.L.Hansen, T.M.Schmeing, P.B.Moore, T.A.Steitz. Structural Insights Into Peptide Bond Formation. Proc.Natl.Acad.Sci.Usa V. 99 11670 2002.
ISSN: ISSN 0027-8424
PubMed: 12185246
DOI: 10.1073/PNAS.172404099