Chlorine in PDB 2lzg: uc(Nmr) Structure of MDM2 (6-125) with Pip-1

The binding sites of Chlorine atom in the uc(Nmr) Structure of MDM2 (6-125) with Pip-1 (pdb code 2lzg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the uc(Nmr) Structure of MDM2 (6-125) with Pip-1, PDB code: 2lzg:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the uc(Nmr) Structure of MDM2 (6-125) with Pip-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of uc(Nmr) Structure of MDM2 (6-125) with Pip-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:20.0 occ:1.00 CL1 A:13Q201 0.0 20.0 1.0 C3 A:13Q201 1.7 20.0 1.0 C4 A:13Q201 2.7 20.0 1.0 C2 A:13Q201 2.7 20.0 1.0 H2 A:13Q201 2.9 20.0 1.0 H3 A:13Q201 2.9 20.0 1.0 HD21 A:LEU57 3.0 2.4 1.0 HD13 A:ILE61 3.0 72.5 1.0 HD12 A:ILE61 3.2 74.1 1.0 HG22 A:ILE99 3.3 54.4 1.0 HB3 A:LEU57 3.4 44.3 1.0 CD1 A:ILE61 3.5 14.1 1.0 HD12 A:LEU57 3.5 0.3 1.0 HD11 A:ILE61 3.6 25.1 1.0 C1 A:13Q201 4.0 20.0 1.0 C5 A:13Q201 4.0 20.0 1.0 CD2 A:LEU57 4.0 2.4 1.0 HD12 A:ILE99 4.0 24.0 1.0 HD13 A:LEU54 4.1 72.1 1.0 HE2 A:PHE91 4.3 71.3 1.0 CG2 A:ILE99 4.3 4.4 1.0 CB A:LEU57 4.3 14.2 1.0 HD11 A:ILE99 4.3 50.4 1.0 HA2 A:GLY58 4.4 1.4 1.0 CD1 A:LEU57 4.4 44.0 1.0 CG A:LEU57 4.5 11.0 1.0 C6 A:13Q201 4.5 20.0 1.0 HZ A:PHE86 4.5 73.4 1.0 HG21 A:ILE99 4.6 33.3 1.0 HD22 A:LEU57 4.6 34.5 1.0 HD23 A:LEU57 4.6 74.0 1.0 HD12 A:LEU54 4.7 72.1 1.0 CD1 A:ILE99 4.7 33.4 1.0 O A:LEU57 4.7 51.2 1.0 HG23 A:ILE99 4.7 45.0 1.0 C A:LEU57 4.7 31.4 1.0 H4 A:13Q201 4.9 20.0 1.0 H1 A:13Q201 4.9 20.0 1.0 CD1 A:LEU54 4.9 51.4 1.0 HG23 A:VAL93 4.9 33.4 1.0 CG1 A:ILE61 4.9 61.0 1.0 N A:GLY58 4.9 22.3 1.0 HD11 A:LEU57 5.0 73.4 1.0 HB2 A:LEU57 5.0 44.5 1.0

Chlorine binding site 2 out of 2 in the uc(Nmr) Structure of MDM2 (6-125) with Pip-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of uc(Nmr) Structure of MDM2 (6-125) with Pip-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:20.0 occ:1.00 CL2 A:13Q201 0.0 20.0 1.0 C15 A:13Q201 1.7 20.0 1.0 C16 A:13Q201 2.7 20.0 1.0 C14 A:13Q201 2.7 20.0 1.0 H11 A:13Q201 2.8 20.0 1.0 H12 A:13Q201 2.9 20.0 1.0 HA A:HIS96 2.9 41.4 1.0 HD12 A:LEU54 3.0 72.1 1.0 HB A:ILE99 3.2 0.4 1.0 HB3 A:HIS96 3.4 2.1 1.0 HD12 A:ILE99 3.4 24.0 1.0 HD2 A:TYR100 3.5 70.4 1.0 HD2 A:HIS96 3.6 51.1 1.0 CA A:HIS96 3.8 53.4 1.0 CD2 A:HIS96 3.8 15.2 1.0 CB A:HIS96 3.8 31.3 1.0 CG A:HIS96 3.9 21.3 1.0 C17 A:13Q201 4.0 20.0 1.0 C12 A:13Q201 4.0 20.0 1.0 CD1 A:LEU54 4.0 51.4 1.0 CD2 A:TYR100 4.1 4.2 1.0 HD22 A:LEU54 4.1 52.4 1.0 O A:HIS96 4.2 74.1 1.0 CB A:ILE99 4.2 55.2 1.0 CD1 A:ILE99 4.3 33.4 1.0 HE2 A:TYR100 4.3 33.3 1.0 H A:TYR100 4.4 22.2 1.0 HD13 A:ILE99 4.4 11.4 1.0 HG A:LEU54 4.4 71.2 1.0 HD11 A:LEU54 4.5 13.2 1.0 C A:HIS96 4.5 3.1 1.0 C13 A:13Q201 4.5 20.0 1.0 CE2 A:TYR100 4.5 44.2 1.0 HG22 A:ILE99 4.5 54.4 1.0 HB2 A:TYR100 4.6 31.5 1.0 HD13 A:LEU54 4.6 72.1 1.0 NE2 A:HIS96 4.6 35.2 1.0 CG A:LEU54 4.7 33.2 1.0 ND1 A:HIS96 4.7 75.0 1.0 HG21 A:ILE99 4.7 33.3 1.0 CG1 A:ILE99 4.8 20.2 1.0 O A:GLU95 4.8 51.2 1.0 CG2 A:ILE99 4.8 4.4 1.0 N A:TYR100 4.8 22.3 1.0 H13 A:13Q201 4.9 20.0 1.0 N A:HIS96 4.9 10.3 1.0 HB2 A:HIS96 4.9 24.4 1.0 CG A:TYR100 4.9 52.1 1.0 CD2 A:LEU54 4.9 2.5 1.0 H A:ILE99 5.0 31.4 1.0 HG13 A:ILE99 5.0 34.1 1.0

K.Michelsen, J.B.Jordan, J.Lewis, A.M.Long, E.Yang, Y.Rew, J.Zhou, P.Yakowec, P.D.Schnier, X.Huang, L.Poppe. Ordering of the N-Terminus of Human MDM2 By Small Molecule Inhibitors. J.Am.Chem.Soc. V. 134 17059 2012.
ISSN: ISSN 0002-7863
PubMed: 22991965
DOI: 10.1021/JA305839B