|
Atomistry » Chlorine » PDB 2xmc-2xs4 » 2xne | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2xmc-2xs4 » 2xne » |
Chlorine in PDB 2xne: Structure of Aurora-A Bound to An Imidazopyrazine InhibitorEnzymatic activity of Structure of Aurora-A Bound to An Imidazopyrazine Inhibitor
All present enzymatic activity of Structure of Aurora-A Bound to An Imidazopyrazine Inhibitor:
2.7.11.1; Protein crystallography data
The structure of Structure of Aurora-A Bound to An Imidazopyrazine Inhibitor, PDB code: 2xne
was solved by
M.Kosmopoulou,
R.Bayliss,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Aurora-A Bound to An Imidazopyrazine Inhibitor
(pdb code 2xne). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Aurora-A Bound to An Imidazopyrazine Inhibitor, PDB code: 2xne: Chlorine binding site 1 out of 1 in 2xneGo back to Chlorine Binding Sites List in 2xne
Chlorine binding site 1 out
of 1 in the Structure of Aurora-A Bound to An Imidazopyrazine Inhibitor
Mono view Stereo pair view
Reference:
N.Bouloc,
J.M.Large,
M.Kosmopoulou,
C.Sun,
A.Faisal,
M.Matteucci,
J.Reynisson,
N.Brown,
B.Atrash,
J.Blagg,
E.Mcdonald,
S.Linardopoulos,
R.Bayliss,
V.Bavetsias.
Structure-Based Design of Imidazo[1,2-A]Pyrazine Derivatives As Selective Inhibitors of Aurora-A Kinase in Cells. Bioorg. Med. Chem. Lett. V. 20 5988 2010.
Page generated: Sat Dec 12 09:26:25 2020
ISSN: ESSN 1464-3405 PubMed: 20833547 DOI: 10.1016/J.BMCL.2010.08.091 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |