Atomistry » Chlorine » PDB 2y5f-2yc5 » 2ya8
Atomistry »
  Chlorine »
    PDB 2y5f-2yc5 »
      2ya8 »

Chlorine in PDB 2ya8: Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate

Enzymatic activity of Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate

All present enzymatic activity of Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate:
3.2.1.18;

Protein crystallography data

The structure of Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate, PDB code: 2ya8 was solved by H.Gut, G.Xu, G.L.Taylor, M.A.Walsh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 24.95 / 1.75
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 165.754, 48.492, 125.183, 90.00, 104.04, 90.00
R / Rfree (%) 18.105 / 22.5

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate (pdb code 2ya8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate, PDB code: 2ya8:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 2ya8

Go back to Chlorine Binding Sites List in 2ya8
Chlorine binding site 1 out of 2 in the Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1778

b:21.0
occ:1.00
NZ A:LYS509 3.1 20.6 1.0
OG A:SER511 3.2 25.6 1.0
N A:SER511 3.3 25.8 1.0
N A:ASN502 3.3 19.7 1.0
N A:THR510 3.4 25.7 1.0
O A:ASN502 3.5 19.2 1.0
CB A:LYS509 3.6 24.9 1.0
CB A:SER511 3.7 26.0 1.0
CA A:GLY501 3.7 22.6 1.0
CG A:LYS509 3.8 24.0 1.0
CE A:LYS509 3.8 23.8 1.0
CA A:LYS509 3.8 24.7 1.0
CD2 A:PHE505 3.9 17.0 1.0
CB A:PHE505 3.9 17.6 1.0
CA A:SER511 4.0 24.7 1.0
C A:GLY501 4.0 21.5 1.0
OG1 A:THR510 4.0 26.1 1.0
C A:LYS509 4.1 25.9 1.0
O A:SER511 4.2 23.3 1.0
C A:THR510 4.2 25.9 1.0
C A:ASN502 4.2 18.6 1.0
CA A:THR510 4.3 26.1 1.0
CG A:PHE505 4.4 17.2 1.0
CA A:ASN502 4.4 19.5 1.0
CD A:LYS509 4.4 23.1 1.0
C A:SER511 4.5 24.1 1.0
O A:HOH2078 4.5 22.0 1.0
O A:LEU500 4.8 25.7 1.0
CB A:THR510 4.8 26.1 1.0
N A:GLY501 4.8 24.5 1.0
CE2 A:PHE505 4.9 18.0 1.0
O A:PHE513 5.0 19.4 1.0
O A:HOH2231 5.0 23.2 1.0

Chlorine binding site 2 out of 2 in 2ya8

Go back to Chlorine Binding Sites List in 2ya8
Chlorine binding site 2 out of 2 in the Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Streptococcus Pneumoniae Nana (TIGR4) in Complex with Oseltamivir Carboxylate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1778

b:20.7
occ:1.00
OG B:SER511 3.1 22.3 1.0
NZ B:LYS509 3.1 19.3 1.0
N B:ASN502 3.2 17.9 1.0
N B:SER511 3.3 22.9 1.0
N B:THR510 3.4 23.2 1.0
O B:ASN502 3.5 16.3 1.0
CA B:GLY501 3.6 20.3 1.0
CB B:LYS509 3.6 21.2 1.0
CB B:SER511 3.7 22.6 1.0
CD2 B:PHE505 3.8 17.9 1.0
CG B:LYS509 3.8 20.5 1.0
CA B:LYS509 3.8 21.6 1.0
CE B:LYS509 3.9 19.2 1.0
OG1 B:THR510 3.9 23.8 1.0
C B:GLY501 3.9 19.2 1.0
CB B:PHE505 3.9 16.9 1.0
CA B:SER511 4.0 22.5 1.0
C B:LYS509 4.1 22.7 1.0
O B:SER511 4.2 23.2 1.0
C B:ASN502 4.2 16.5 1.0
C B:THR510 4.3 23.5 1.0
CA B:ASN502 4.3 16.7 1.0
CG B:PHE505 4.3 15.9 1.0
CA B:THR510 4.3 23.6 1.0
CD B:LYS509 4.5 19.9 1.0
O B:HOH2058 4.5 22.8 1.0
C B:SER511 4.5 22.6 1.0
O B:LEU500 4.7 23.0 1.0
CE2 B:PHE505 4.7 16.4 1.0
CB B:THR510 4.8 23.1 1.0
N B:GLY501 4.8 21.5 1.0
O B:HOH2232 4.9 23.6 1.0
O B:PHE513 5.0 18.4 1.0

Reference:

H.Gut, G.Xu, G.L.Taylor, M.A.Walsh. Structural Basis For Streptococcus Pneumoniae Nana Inhibition By Influenza Antivirals Zanamivir and Oseltamivir Carboxylate. J.Mol.Biol. V. 409 496 2011.
ISSN: ISSN 0022-2836
PubMed: 21514303
DOI: 10.1016/J.JMB.2011.04.016
Page generated: Fri Jul 11 02:33:28 2025

Last articles

Cl in 3OUG
Cl in 3OWL
Cl in 3OWK
Cl in 3OWD
Cl in 3OWB
Cl in 3OUI
Cl in 3OVX
Cl in 3OVZ
Cl in 3OV8
Cl in 3OVE
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy