Chlorine in PDB 2z7s: Crystal Structure of the N-Terminal Kinase Domain of Human RSK1 Bound to Purvalnol A

All present enzymatic activity of Crystal Structure of the N-Terminal Kinase Domain of Human RSK1 Bound to Purvalnol A:
2.7.11.1;

The structure of Crystal Structure of the N-Terminal Kinase Domain of Human RSK1 Bound to Purvalnol A, PDB code: 2z7s was solved by M.Ikuta, S.K.Munshi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	51.641, 52.996, 119.304, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Chlorine atom in the Crystal Structure of the N-Terminal Kinase Domain of Human RSK1 Bound to Purvalnol A (pdb code 2z7s). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the N-Terminal Kinase Domain of Human RSK1 Bound to Purvalnol A, PDB code: 2z7s:

Chlorine binding site 1 out of 1 in the Crystal Structure of the N-Terminal Kinase Domain of Human RSK1 Bound to Purvalnol A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the N-Terminal Kinase Domain of Human RSK1 Bound to Purvalnol A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:64.9 occ:1.00 CL1 A:P011 0.0 64.9 1.0 C5A A:P011 1.8 57.0 1.0 C6A A:P011 2.7 54.1 1.0 C4A A:P011 2.8 56.7 1.0 O A:HOH399 3.7 66.6 1.0 C1A A:P011 4.1 51.5 1.0 C3A A:P011 4.1 55.8 1.0 O A:LEU68 4.1 77.5 1.0 C2A A:P011 4.6 52.9 1.0 CG A:LEU68 4.7 73.7 1.0 C27 A:P011 4.8 58.6 1.0 C A:LEU68 4.9 77.4 1.0 CB A:LEU68 5.0 74.6 1.0

M.Ikuta, M.Kornienko, N.Byrne, J.C.Reid, S.Mizuarai, H.Kotani, S.K.Munshi. Crystal Structures of the N-Terminal Kinase Domain of Human RSK1 Bound to Three Different Ligands: Implications For the Design of RSK1 Specific Inhibitors. Protein Sci. V. 16 2626 2007.
ISSN: ISSN 0961-8368
PubMed: 17965187
DOI: 10.1110/PS.073123707