Chlorine in PDB 3bbr: Crystal Structure of the IGLUR2 Ligand Binding Core (S1S2J-N775S) in Complex with A Dimeric Positive Modulator As Well As Glutamate at 2.25 A Resolution

The structure of Crystal Structure of the IGLUR2 Ligand Binding Core (S1S2J-N775S) in Complex with A Dimeric Positive Modulator As Well As Glutamate at 2.25 A Resolution, PDB code: 3bbr was solved by J.S.Kastrup, M.Gajhede, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.43 / 2.25
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	99.080, 121.780, 47.427, 90.00, 90.00, 90.00
R / Rfree (%)	16.9 / 23.1

The binding sites of Chlorine atom in the Crystal Structure of the IGLUR2 Ligand Binding Core (S1S2J-N775S) in Complex with A Dimeric Positive Modulator As Well As Glutamate at 2.25 A Resolution (pdb code 3bbr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the IGLUR2 Ligand Binding Core (S1S2J-N775S) in Complex with A Dimeric Positive Modulator As Well As Glutamate at 2.25 A Resolution, PDB code: 3bbr:

Chlorine binding site 1 out of 1 in the Crystal Structure of the IGLUR2 Ligand Binding Core (S1S2J-N775S) in Complex with A Dimeric Positive Modulator As Well As Glutamate at 2.25 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the IGLUR2 Ligand Binding Core (S1S2J-N775S) in Complex with A Dimeric Positive Modulator As Well As Glutamate at 2.25 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl266 b:34.3 occ:1.00 N A:ASN22 3.5 4.5 1.0 O A:HOH412 3.7 10.1 1.0 CA A:LYS21 4.1 9.6 1.0 CD2 A:HIS23 4.1 5.8 1.0 O A:HOH298 4.2 20.0 1.0 C A:LYS21 4.3 7.7 1.0 CA A:ASN22 4.4 5.8 1.0 NE2 A:HIS23 4.5 8.2 1.0 O A:LYS20 4.5 7.5 1.0 CD A:LYS21 4.7 34.5 1.0 N A:HIS23 4.9 5.0 1.0 CB A:LYS21 5.0 11.0 1.0

B.H.Kaae, K.Harpsoe, J.S.Kastrup, A.C.Sanz, D.S.Pickering, B.Metzler, R.P.Clausen, M.Gajhede, P.Sauerberg, T.Liljefors, U.Madsen. Structural Proof of A Dimeric Positive Modulator Bridging Two Identical Ampa Receptor-Binding Sites Chem.Biol. V. 14 1294 2007.
ISSN: ISSN 1074-5521
PubMed: 18022568
DOI: 10.1016/J.CHEMBIOL.2007.10.012