Chlorine in PDB 3k2j: Crystal Structure of the 3RD Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1)

The structure of Crystal Structure of the 3RD Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1), PDB code: 3k2j was solved by P.Filippakopoulos, S.Picaud, T.Keates, A.Chaikuad, A.C.W.Pike, T.Krojer, R.Sethi, F.Von Delft, C.H.Arrowsmith, A.Edwards, J.Weigelt, C.Bountra, S.Knapp, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.22 / 2.20
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	81.390, 81.390, 79.475, 90.00, 90.00, 120.00
R / Rfree (%)	22.4 / 27

The binding sites of Chlorine atom in the Crystal Structure of the 3RD Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) (pdb code 3k2j). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the 3RD Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1), PDB code: 3k2j:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the 3RD Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the 3RD Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:69.6 occ:1.00 N A:GLY346 3.5 35.0 1.0 O A:ASP344 4.0 26.8 1.0 CA A:LEU345 4.2 35.4 1.0 CA A:GLY346 4.3 32.4 1.0 C A:LEU345 4.3 35.7 1.0 C A:ASP344 4.9 26.9 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the 3RD Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the 3RD Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl2 b:71.1 occ:1.00 CD A:PRO375 4.0 30.2 1.0 OE1 A:GLU374 4.1 44.4 1.0 CG A:PRO375 4.2 27.1 1.0 CB A:GLU374 4.4 32.1 1.0 N A:PRO375 4.5 30.0 1.0 CB A:PRO375 4.8 28.2 1.0 NH2 A:ARG440 4.8 42.5 1.0 CA A:PRO375 4.9 28.6 1.0 C A:GLU374 5.0 26.0 1.0 CD A:GLU374 5.0 39.6 1.0

P.Filippakopoulos, S.Picaud, T.Keates, A.Chaikuad, A.C.W.Pike, T.Krojer, R.Sethi, F.Von Delft, C.H.Arrowsmith, A.Edwards, J.Weigelt, C.Bountra, S.Knapp. Crystal Structure of the 3RD Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) To Be Published.