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Chlorine in PDB 3lms: Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci.

Enzymatic activity of Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci.

All present enzymatic activity of Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci.:
3.4.17.20;

Protein crystallography data

The structure of Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci., PDB code: 3lms was solved by L.Sanglas, J.L.Arolas, Z.Valnickova, F.X.Aviles, J.J.Enghild, F.X.Gomis-Ruth, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.18 / 2.50
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 157.180, 157.180, 57.070, 90.00, 90.00, 120.00
R / Rfree (%) 18.5 / 21.6

Other elements in 3lms:

The structure of Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci. also contains other interesting chemical elements:

Potassium (K) 2 atoms
Calcium (Ca) 1 atom
Zinc (Zn) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci. (pdb code 3lms). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci., PDB code: 3lms:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 3lms

Go back to Chlorine Binding Sites List in 3lms
Chlorine binding site 1 out of 3 in the Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl506

b:42.6
occ:1.00
OH A:TYR118 3.6 38.7 1.0
O A:HOH596 4.0 49.5 1.0
O A:HOH556 4.2 48.5 1.0
CZ A:TYR118 4.6 41.8 1.0
CL A:CL507 4.7 39.3 1.0
CG2 B:THR29 4.7 46.7 1.0
CD A:LYS122 4.7 45.1 1.0
CE1 A:TYR118 4.8 40.2 1.0
O A:HOH549 4.8 41.0 1.0

Chlorine binding site 2 out of 3 in 3lms

Go back to Chlorine Binding Sites List in 3lms
Chlorine binding site 2 out of 3 in the Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl507

b:39.3
occ:1.00
CA A:CA509 2.9 63.9 1.0
NZ A:LYS122 3.8 45.7 1.0
O A:HOH596 4.0 49.5 1.0
CE A:LYS122 4.1 45.7 1.0
CL A:CL506 4.7 42.6 1.0

Chlorine binding site 3 out of 3 in 3lms

Go back to Chlorine Binding Sites List in 3lms
Chlorine binding site 3 out of 3 in the Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor, Tafia, in Complex with Tick-Derived Funnelin Inhibitor, Tci. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl508

b:52.1
occ:1.00
CA A:CA509 2.9 63.9 1.0
OG B:SER28 3.1 51.2 1.0
O B:HOH516 3.4 53.5 1.0
CB B:SER28 3.7 50.7 1.0
CE A:LYS122 3.8 45.7 1.0
NZ A:LYS122 4.0 45.7 1.0

Reference:

L.Sanglas, J.L.Arolas, Z.Valnickova, F.X.Aviles, J.J.Enghild, F.X.Gomis-Ruth. Insights Into the Molecular Inactivation Mechanism of Human Activated Thrombin-Activatable Fibrinolysis Inhibitor J.Thromb.Haemost. V. 8 1056 2010.
ISSN: ISSN 1538-7933
PubMed: 20088943
DOI: 10.1111/J.1538-7836.2010.03740.X
Page generated: Sat Dec 12 09:53:22 2020

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