Chlorine in PDB 3mmk: The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification

The structure of The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification, PDB code: 3mmk was solved by M.S.Gadd, D.B.Langley, J.M.Guss, J.M.Matthews, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.14 / 2.16
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	46.823, 88.734, 49.851, 90.00, 111.85, 90.00
R / Rfree (%)	23.5 / 26.5

The structure of The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification also contains other interesting chemical elements:

Zinc

(Zn)

8 atoms

The binding sites of Chlorine atom in the The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification (pdb code 3mmk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification, PDB code: 3mmk:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl170 b:82.8 occ:1.00 CG A:PRO28 3.4 53.3 1.0 CD A:PRO28 3.9 48.6 1.0 NE2 A:HIS49 3.9 60.5 1.0 O A:GLN26 4.1 68.6 1.0 CD1 A:ILE42 4.1 53.1 1.0 CD2 A:HIS49 4.2 58.9 1.0 OE1 A:GLN295 4.2 81.8 1.0 CE1 A:HIS49 4.5 62.1 1.0 CB A:PRO28 4.8 52.8 1.0 CG2 A:ILE42 4.9 52.4 1.0 CD A:GLN295 5.0 80.7 1.0 CG A:HIS49 5.0 56.4 1.0

Chlorine binding site 2 out of 4 in the The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl171 b:87.9 occ:1.00 O A:HOH185 3.0 59.8 1.0 OG1 A:THR126 3.3 55.5 1.0 N A:THR126 3.3 49.0 1.0 NH2 A:ARG103 3.5 52.4 1.0 CB A:ALA125 3.7 41.7 1.0 CB A:THR126 3.8 51.3 1.0 CA A:ALA125 4.0 41.7 1.0 CA A:THR126 4.1 47.6 1.0 C A:ALA125 4.1 50.2 1.0 CZ A:ARG103 4.5 49.2 1.0 NH1 A:ARG103 4.6 48.3 1.0 O A:THR126 4.9 47.5 1.0

Chlorine binding site 3 out of 4 in the The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl172 b:79.8 occ:1.00 N A:LYS40 3.3 44.8 1.0 CB A:LYS40 3.5 52.7 1.0 CA A:LYS40 4.1 47.6 1.0 CA A:ASP39 4.3 45.2 1.0 C A:ASP39 4.3 45.9 1.0 CB A:ASP39 4.8 50.3 1.0 CG A:LYS40 4.9 55.1 1.0 OD2 A:ASP39 4.9 57.9 1.0 N A:PHE41 5.0 46.7 1.0

Chlorine binding site 4 out of 4 in the The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl170 b:76.6 occ:1.00 NE2 B:GLN295 3.7 70.1 1.0 NZ B:LYS44 3.7 69.0 1.0 NE2 B:HIS49 3.7 62.5 1.0 CE1 B:HIS49 4.0 65.1 1.0 OE1 B:GLN295 4.0 68.1 1.0 CD B:GLN295 4.3 67.5 1.0 CE B:LYS44 4.3 67.3 1.0 CD B:LYS44 4.7 67.0 1.0

M.S.Gadd, M.Bhati, C.M.Jeffries, D.B.Langley, J.Trewhella, J.M.Guss, J.M.Matthews. The Structural Basis For Partial Redundancy in A Class of Transcription Factors, the Lim-Homeodomain Proteins, in Neural Cell Type Specification. J.Biol.Chem. 2011.
ISSN: ESSN 1083-351X
PubMed: 22025611
DOI: 10.1074/JBC.M111.248559