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Atomistry » Chlorine » PDB 3ser-3smc » 3sfh | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3ser-3smc » 3sfh » |
Chlorine in PDB 3sfh: Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived InhibitorEnzymatic activity of Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor
All present enzymatic activity of Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor:
3.5.1.98; Protein crystallography data
The structure of Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor, PDB code: 3sfh
was solved by
T.Stams,
B.Vash,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3sfh:
The structure of Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor
(pdb code 3sfh). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor, PDB code: 3sfh: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 3sfhGo back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 3sfhGo back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Crystal Structure of Human HDAC8 Inhibitor Complex, An Amino Acid Derived Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
L.Whitehead,
M.R.Dobler,
B.Radetich,
Y.Zhu,
P.W.Atadja,
T.Claiborne,
J.E.Grob,
A.Mcriner,
M.R.Pancost,
A.Patnaik,
W.Shao,
M.Shultz,
R.Tichkule,
R.A.Tommasi,
B.Vash,
P.Wang,
T.Stams.
Human Hdac Isoform Selectivity Achieved Via Exploitation of the Acetate Release Channel with Structurally Unique Small Molecule Inhibitors. Bioorg.Med.Chem. V. 19 4626 2011.
Page generated: Fri Jul 11 10:17:58 2025
ISSN: ISSN 0968-0896 PubMed: 21723733 DOI: 10.1016/J.BMC.2011.06.030 |
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