Chlorine in PDB 4cns: Crystal Structure of Truncated Human Crmp-4

The structure of Crystal Structure of Truncated Human Crmp-4, PDB code: 4cns was solved by R.Ponnusamy, B.Lohkamp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.99 / 2.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	86.400, 89.620, 133.100, 90.00, 101.40, 90.00
R / Rfree (%)	18.904 / 22.581

The structure of Crystal Structure of Truncated Human Crmp-4 also contains other interesting chemical elements:

Magnesium

(Mg)

5 atoms

The binding sites of Chlorine atom in the Crystal Structure of Truncated Human Crmp-4 (pdb code 4cns). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Truncated Human Crmp-4, PDB code: 4cns:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of Truncated Human Crmp-4


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Truncated Human Crmp-4 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1493 b:28.1 occ:1.00 O A:HOH2067 3.1 14.0 1.0 N A:TYR170 3.2 14.4 1.0 NH2 A:ARG227 3.4 14.2 1.0 NH1 A:ARG227 3.5 14.4 1.0 CG2 A:ILE205 3.7 14.4 1.0 CB A:ALA169 3.8 12.5 1.0 CA A:TYR170 3.8 15.5 1.0 CZ A:ARG227 3.8 14.2 1.0 CD1 A:TYR170 4.0 16.7 1.0 CA A:GLY202 4.1 15.2 1.0 C A:ALA169 4.2 13.6 1.0 CB A:ILE205 4.2 13.9 1.0 CA A:ALA169 4.2 12.8 1.0 CD1 A:ILE205 4.2 13.6 1.0 CE1 A:TYR170 4.3 17.1 1.0 CG A:TYR170 4.4 16.8 1.0 O A:GLY202 4.7 17.2 1.0 CB A:TYR170 4.8 15.5 1.0 N A:LYS171 4.8 17.0 1.0 CG1 A:ILE205 4.8 13.8 1.0 C A:TYR170 4.9 16.6 1.0 CZ A:TYR170 4.9 17.2 1.0 C A:GLY202 4.9 16.1 1.0 NE2 A:GLN209 5.0 16.5 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of Truncated Human Crmp-4


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Truncated Human Crmp-4 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1489 b:16.9 occ:1.00 N B:TYR170 3.2 15.2 1.0 NH2 B:ARG227 3.4 16.0 1.0 NH1 B:ARG227 3.5 15.6 1.0 CA B:TYR170 3.7 16.5 1.0 CD1 B:TYR170 3.7 17.5 1.0 CG2 B:ILE205 3.8 15.6 1.0 CZ B:ARG227 3.8 15.2 1.0 CB B:ALA169 3.9 14.9 1.0 CE1 B:TYR170 4.1 17.6 1.0 CG B:TYR170 4.2 17.4 1.0 C B:ALA169 4.3 14.1 1.0 CA B:GLY202 4.3 12.7 1.0 CB B:ILE205 4.3 14.9 1.0 CA B:ALA169 4.4 14.2 1.0 CD1 B:ILE205 4.4 14.8 1.0 CB B:TYR170 4.6 17.1 1.0 N B:LYS171 4.7 20.1 1.0 CZ B:TYR170 4.8 17.4 1.0 O B:GLY202 4.8 14.0 1.0 C B:TYR170 4.8 18.2 1.0 NE2 B:GLN209 4.9 17.8 1.0 CD2 B:TYR170 4.9 17.1 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of Truncated Human Crmp-4


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Truncated Human Crmp-4 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1490 b:23.9 occ:1.00 O C:HOH2046 2.9 8.5 1.0 N C:TYR170 3.2 15.7 1.0 NH2 C:ARG227 3.4 14.7 1.0 NH1 C:ARG227 3.5 15.4 1.0 CG2 C:ILE205 3.7 16.1 1.0 CA C:TYR170 3.8 16.8 1.0 CB C:ALA169 3.8 14.6 1.0 CZ C:ARG227 3.9 15.0 1.0 CD1 C:TYR170 3.9 16.8 1.0 CA C:GLY202 4.1 15.3 1.0 CB C:ILE205 4.2 16.2 1.0 CE1 C:TYR170 4.2 17.3 1.0 C C:ALA169 4.2 15.1 1.0 CD1 C:ILE205 4.2 14.8 1.0 CA C:ALA169 4.2 15.2 1.0 CG C:TYR170 4.3 16.6 1.0 O C:GLY202 4.7 16.5 1.0 CB C:TYR170 4.7 16.8 1.0 N C:LYS171 4.8 18.7 1.0 CG1 C:ILE205 4.8 15.6 1.0 NE2 C:GLN209 4.8 14.7 1.0 C C:TYR170 4.8 17.4 1.0 CZ C:TYR170 4.9 16.6 1.0 C C:GLY202 4.9 16.1 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of Truncated Human Crmp-4


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Truncated Human Crmp-4 within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1490 b:19.2 occ:1.00 O D:HOH2061 2.9 8.8 1.0 N D:TYR170 3.2 15.8 1.0 NH2 D:ARG227 3.4 16.8 1.0 NH1 D:ARG227 3.5 17.9 1.0 CA D:TYR170 3.7 16.6 1.0 CG2 D:ILE205 3.7 14.8 1.0 CB D:ALA169 3.8 14.9 1.0 CD1 D:TYR170 3.8 16.6 1.0 CZ D:ARG227 3.8 17.4 1.0 CE1 D:TYR170 4.1 16.8 1.0 CA D:GLY202 4.2 15.4 1.0 C D:ALA169 4.2 14.7 1.0 CB D:ILE205 4.2 14.8 1.0 CG D:TYR170 4.2 16.2 1.0 CA D:ALA169 4.3 14.4 1.0 CD1 D:ILE205 4.3 14.2 1.0 CB D:TYR170 4.6 16.4 1.0 O D:GLY202 4.7 16.5 1.0 N D:LYS171 4.7 20.0 1.0 C D:TYR170 4.8 17.8 1.0 CZ D:TYR170 4.8 17.0 1.0 CG1 D:ILE205 4.9 14.7 1.0 NE2 D:GLN209 4.9 17.0 1.0 CD2 D:TYR170 4.9 16.3 1.0 C D:GLY202 5.0 16.0 1.0

R.Ponnusamy, A.Lebedev, S.Pahlow, B.Lohkamp. Crystal Structure of Human Crmp-4: Correction of Intensities For Lattice-Translocation Disorder Acta Crystallogr.,Sect.D V. 70 1680 2014.
ISSN: ISSN 0907-4449
PubMed: 24914979
DOI: 10.1107/S1399004714006634