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Atomistry » Chlorine » PDB 4e0j-4e9v » 4e26 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4e0j-4e9v » 4e26 » |
Chlorine in PDB 4e26: Braf in Complex with An Organic Inhibitor 7898734Enzymatic activity of Braf in Complex with An Organic Inhibitor 7898734
All present enzymatic activity of Braf in Complex with An Organic Inhibitor 7898734:
2.7.11.1; Protein crystallography data
The structure of Braf in Complex with An Organic Inhibitor 7898734, PDB code: 4e26
was solved by
J.Qin,
P.Xie,
C.Ventocilla,
G.Zhou,
A.Vultur,
Q.Chen,
M.Herlyn,
J.Winkler,
R.Marmorstein,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Braf in Complex with An Organic Inhibitor 7898734
(pdb code 4e26). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Braf in Complex with An Organic Inhibitor 7898734, PDB code: 4e26: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4e26Go back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Braf in Complex with An Organic Inhibitor 7898734
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 4e26Go back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Braf in Complex with An Organic Inhibitor 7898734
![]() Mono view ![]() Stereo pair view
Reference:
J.Qin,
P.Xie,
C.Ventocilla,
G.Zhou,
A.Vultur,
Q.Chen,
Q.Liu,
M.Herlyn,
J.Winkler,
R.Marmorstein.
Identification of A Novel Family of Braf(V600E) Inhibitors. J.Med.Chem. V. 55 5220 2012.
Page generated: Fri Jul 11 14:35:47 2025
ISSN: ISSN 0022-2623 PubMed: 22537109 DOI: 10.1021/JM3004416 |
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