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Chlorine in PDB 4gki: Crystal Structure of the Aminoglycoside Phosphotransferase Aph(3')-Ia, with Substrate Kanamycin and Small Molecule Inhibitor 1-Nm-PP1Enzymatic activity of Crystal Structure of the Aminoglycoside Phosphotransferase Aph(3')-Ia, with Substrate Kanamycin and Small Molecule Inhibitor 1-Nm-PP1
All present enzymatic activity of Crystal Structure of the Aminoglycoside Phosphotransferase Aph(3')-Ia, with Substrate Kanamycin and Small Molecule Inhibitor 1-Nm-PP1:
2.7.1.95; Protein crystallography data
The structure of Crystal Structure of the Aminoglycoside Phosphotransferase Aph(3')-Ia, with Substrate Kanamycin and Small Molecule Inhibitor 1-Nm-PP1, PDB code: 4gki
was solved by
P.J.Stogios,
E.Evdokimova,
Z.Wawrzak,
G.Minasov,
O.Egorova,
R.Di Leo,
T.Shakya,
P.Spanogiannopoulos,
N.Todorovic,
A.Capretta,
G.D.Wright,
A.Savchenko,
W.F.Anderson,
Center For Structural Genomics Ofinfectious Diseases (Csgid),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4gki:
The structure of Crystal Structure of the Aminoglycoside Phosphotransferase Aph(3')-Ia, with Substrate Kanamycin and Small Molecule Inhibitor 1-Nm-PP1 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the Aminoglycoside Phosphotransferase Aph(3')-Ia, with Substrate Kanamycin and Small Molecule Inhibitor 1-Nm-PP1
(pdb code 4gki). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Aminoglycoside Phosphotransferase Aph(3')-Ia, with Substrate Kanamycin and Small Molecule Inhibitor 1-Nm-PP1, PDB code: 4gki: Chlorine binding site 1 out of 1 in 4gkiGo back to Chlorine Binding Sites List in 4gki
Chlorine binding site 1 out
of 1 in the Crystal Structure of the Aminoglycoside Phosphotransferase Aph(3')-Ia, with Substrate Kanamycin and Small Molecule Inhibitor 1-Nm-PP1
Mono view Stereo pair view
Reference:
P.J.Stogios,
P.Spanogiannopoulos,
E.Evdokimova,
O.Egorova,
T.Shakya,
N.Todorovic,
A.Capretta,
G.D.Wright,
A.Savchenko.
Structure-Guided Optimization of Protein Kinase Inhibitors Reverses Aminoglycoside Antibiotic Resistance. Biochem.J. V. 454 191 2013.
Page generated: Sat Dec 12 10:40:06 2020
ISSN: ISSN 0264-6021 PubMed: 23758273 DOI: 10.1042/BJ20130317 |
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