Chlorine in PDB 4z8n: Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A)

The structure of Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A), PDB code: 4z8n was solved by J.Gruszczyk, W.H.Tham, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.84 / 2.12
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	58.790, 93.450, 126.720, 90.00, 90.00, 90.00
R / Rfree (%)	20.3 / 22.9

The structure of Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A) also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Calcium	(Ca)	1 atom

The binding sites of Chlorine atom in the Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A) (pdb code 4z8n). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A), PDB code: 4z8n:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Erythrocyte-Binding Domain From Plasmodium Vivax Reticulocyte-Binding Protein 2A (PVRBP2A) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:84.0 occ:1.00 CG2 B:THR431 4.1 49.8 1.0 CA A:TYR330 4.1 39.9 1.0 N A:TYR330 4.3 42.1 1.0 O A:ASN329 4.4 38.8 1.0 C A:ASN329 4.4 43.4 1.0 CE1 B:TYR327 4.5 53.3 1.0 CB A:TYR330 4.5 40.7 1.0 CD1 A:TYR330 4.5 47.2 1.0 OG1 A:THR333 4.7 44.7 1.0 CB A:ASN329 4.8 52.6 1.0 CB A:THR333 4.8 40.2 1.0 CB B:THR431 4.9 46.9 1.0 O A:HOH671 4.9 59.9 1.0 CD1 B:TYR327 5.0 51.0 1.0

J.Gruszczyk, N.T.Lim, A.Arnott, W.Q.He, W.Nguitragool, W.Roobsoong, Y.F.Mok, J.M.Murphy, K.R.Smith, S.Lee, M.Bahlo, I.Mueller, A.E.Barry, W.H.Tham. Structurally Conserved Erythrocyte-Binding Domain in Plasmodium Provides A Versatile Scaffold For Alternate Receptor Engagement. Proc.Natl.Acad.Sci.Usa V. 113 E191 2016.
ISSN: ESSN 1091-6490
PubMed: 26715754
DOI: 10.1073/PNAS.1516512113