Chlorine in PDB 5fwe: JMJD2A Complexed with Ni(II), Nog and Histone H4(1-15)R3ME2S Peptide

The structure of JMJD2A Complexed with Ni(II), Nog and Histone H4(1-15)R3ME2S Peptide, PDB code: 5fwe was solved by R.Chowdhury, L.J.Walport, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.85 / 2.05
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	100.739, 149.400, 57.372, 90.00, 90.00, 90.00
R / Rfree (%)	23.4 / 25.5

The structure of JMJD2A Complexed with Ni(II), Nog and Histone H4(1-15)R3ME2S Peptide also contains other interesting chemical elements:

Nickel	(Ni)	2 atoms
Zinc	(Zn)	2 atoms

The binding sites of Chlorine atom in the JMJD2A Complexed with Ni(II), Nog and Histone H4(1-15)R3ME2S Peptide (pdb code 5fwe). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the JMJD2A Complexed with Ni(II), Nog and Histone H4(1-15)R3ME2S Peptide, PDB code: 5fwe:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the JMJD2A Complexed with Ni(II), Nog and Histone H4(1-15)R3ME2S Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of JMJD2A Complexed with Ni(II), Nog and Histone H4(1-15)R3ME2S Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1357 b:64.8 occ:1.00 N A:GLY229 3.2 50.9 1.0 N A:SER230 3.4 42.2 1.0 CA A:PHE227 3.4 39.3 1.0 C A:PHE227 3.4 44.2 1.0 CA A:GLY229 3.6 51.8 1.0 OG A:SER230 3.7 46.1 1.0 N A:PRO228 3.8 50.3 1.0 CB A:PHE227 3.8 36.5 1.0 O A:PHE227 3.8 44.9 1.0 C A:GLY229 4.0 51.1 1.0 CD A:PRO228 4.2 52.1 1.0 C A:PRO228 4.2 49.1 1.0 CD1 A:PHE227 4.3 42.0 1.0 CB A:SER230 4.4 44.2 1.0 CA A:SER230 4.5 45.6 1.0 CG A:PHE227 4.6 36.8 1.0 CA A:PRO228 4.6 50.4 1.0 N A:PHE227 4.7 43.0 1.0 O A:PHE226 4.8 48.7 1.0 CG A:PRO228 4.8 55.6 1.0

Chlorine binding site 2 out of 2 in the JMJD2A Complexed with Ni(II), Nog and Histone H4(1-15)R3ME2S Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of JMJD2A Complexed with Ni(II), Nog and Histone H4(1-15)R3ME2S Peptide within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1358 b:64.9 occ:1.00 N B:GLY229 3.2 41.8 1.0 C B:PHE227 3.5 34.6 1.0 CA B:PHE227 3.5 35.3 1.0 CA B:GLY229 3.7 46.4 1.0 N B:PRO228 3.7 40.6 1.0 N B:SER230 3.7 40.8 1.0 CD B:PRO228 3.9 39.3 1.0 O B:PHE227 4.0 33.7 1.0 CB B:PHE227 4.0 30.1 1.0 OG B:SER230 4.1 36.9 1.0 C B:GLY229 4.2 45.3 1.0 C B:PRO228 4.3 43.3 1.0 CD1 B:PHE227 4.4 38.0 1.0 CG B:PRO228 4.5 42.2 1.0 CA B:PRO228 4.5 41.7 1.0 O B:PHE226 4.7 39.2 1.0 CG B:PHE227 4.7 36.7 1.0 CB B:SER230 4.8 36.6 1.0 N B:PHE227 4.8 38.0 1.0 CA B:SER230 4.9 37.8 1.0

L.J.Walport, R.J.Hopkinson, R.Chowdhury, R.Schiller, W.Ge, A.Kawamura, C.J.Schofield. Arginine Demethylation Is Catalysed By A Subset of Jmjc Histone Lysine Demethylases. Nat.Commun. V. 7 11974 2016.
ISSN: ESSN 2041-1723
PubMed: 27337104
DOI: 10.1038/NCOMMS11974