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Atomistry » Chlorine » PDB 5on8-5os0 » 5oor » |
Chlorine in PDB 5oor: Structure of CHK1 10-Pt. Mutant Complex with StaurosporineEnzymatic activity of Structure of CHK1 10-Pt. Mutant Complex with Staurosporine
All present enzymatic activity of Structure of CHK1 10-Pt. Mutant Complex with Staurosporine:
2.7.11.1; Protein crystallography data
The structure of Structure of CHK1 10-Pt. Mutant Complex with Staurosporine, PDB code: 5oor
was solved by
P.Dokurno,
D.S.Williamson,
P.Acheson-Dossang,
I.Chen,
J.B.Murray,
T.Shaw,
A.E.Surgenor,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of CHK1 10-Pt. Mutant Complex with Staurosporine
(pdb code 5oor). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of CHK1 10-Pt. Mutant Complex with Staurosporine, PDB code: 5oor: Chlorine binding site 1 out of 1 in 5oorGo back to Chlorine Binding Sites List in 5oor
Chlorine binding site 1 out
of 1 in the Structure of CHK1 10-Pt. Mutant Complex with Staurosporine
Mono view Stereo pair view
Reference:
D.S.Williamson,
G.P.Smith,
P.Acheson-Dossang,
S.T.Bedford,
V.Chell,
I.J.Chen,
J.C.A.Daechsel,
Z.Daniels,
L.David,
P.Dokurno,
M.Hentzer,
M.C.Herzig,
R.E.Hubbard,
J.D.Moore,
J.B.Murray,
S.Newland,
S.C.Ray,
T.Shaw,
A.E.Surgenor,
L.Terry,
K.Thirstrup,
Y.Wang,
K.V.Christensen.
Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using A Crystallographic Surrogate Derived From Checkpoint Kinase 1 (CHK1). J. Med. Chem. V. 60 8945 2017.
Page generated: Sat Dec 12 12:13:07 2020
ISSN: ISSN 1520-4804 PubMed: 29023112 DOI: 10.1021/ACS.JMEDCHEM.7B01186 |
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