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Atomistry » Chlorine » PDB 5on8-5os0 » 5oq6 » |
Chlorine in PDB 5oq6: Structure of CHK1 12-Pt. Mutant Complex with Aminopyrimido- Benzodiazepinone LRRK2 InhibitorEnzymatic activity of Structure of CHK1 12-Pt. Mutant Complex with Aminopyrimido- Benzodiazepinone LRRK2 Inhibitor
All present enzymatic activity of Structure of CHK1 12-Pt. Mutant Complex with Aminopyrimido- Benzodiazepinone LRRK2 Inhibitor:
2.7.11.1; Protein crystallography data
The structure of Structure of CHK1 12-Pt. Mutant Complex with Aminopyrimido- Benzodiazepinone LRRK2 Inhibitor, PDB code: 5oq6
was solved by
P.Dokurno,
D.S.Williamson,
P.Acheson-Dossang,
I.Chen,
J.B.Murray,
T.Shaw,
A.E.Surgenor,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of CHK1 12-Pt. Mutant Complex with Aminopyrimido- Benzodiazepinone LRRK2 Inhibitor
(pdb code 5oq6). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of CHK1 12-Pt. Mutant Complex with Aminopyrimido- Benzodiazepinone LRRK2 Inhibitor, PDB code: 5oq6: Chlorine binding site 1 out of 1 in 5oq6Go back to Chlorine Binding Sites List in 5oq6
Chlorine binding site 1 out
of 1 in the Structure of CHK1 12-Pt. Mutant Complex with Aminopyrimido- Benzodiazepinone LRRK2 Inhibitor
Mono view Stereo pair view
Reference:
D.S.Williamson,
G.P.Smith,
P.Acheson-Dossang,
S.T.Bedford,
V.Chell,
I.J.Chen,
J.C.A.Daechsel,
Z.Daniels,
L.David,
P.Dokurno,
M.Hentzer,
M.C.Herzig,
R.E.Hubbard,
J.D.Moore,
J.B.Murray,
S.Newland,
S.C.Ray,
T.Shaw,
A.E.Surgenor,
L.Terry,
K.Thirstrup,
Y.Wang,
K.V.Christensen.
Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using A Crystallographic Surrogate Derived From Checkpoint Kinase 1 (CHK1). J. Med. Chem. V. 60 8945 2017.
Page generated: Sat Dec 12 12:13:18 2020
ISSN: ISSN 1520-4804 PubMed: 29023112 DOI: 10.1021/ACS.JMEDCHEM.7B01186 |
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