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Chlorine in PDB 6c73: Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site

Enzymatic activity of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site

All present enzymatic activity of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site:
4.2.1.20;

Protein crystallography data

The structure of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site, PDB code: 6c73 was solved by E.Hilario, M.F.Dunn, L.J.Mueller, L.Fan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.82 / 1.65
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 181.609, 58.980, 67.150, 90.00, 94.40, 90.00
R / Rfree (%) 13.8 / 18.3

Other elements in 6c73:

The structure of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site also contains other interesting chemical elements:

Fluorine (F) 3 atoms
Caesium (Cs) 5 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site (pdb code 6c73). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site, PDB code: 6c73:

Chlorine binding site 1 out of 1 in 6c73

Go back to Chlorine Binding Sites List in 6c73
Chlorine binding site 1 out of 1 in the Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl)-2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl420

b:65.5
occ:1.00
O B:HOH919 4.0 38.1 1.0
O B:HOH1009 4.5 40.4 1.0
O B:HOH889 4.6 16.4 1.0
O B:HOH929 4.6 23.8 1.0
O B:HOH994 4.6 22.9 1.0
O B:HOH987 4.7 44.3 1.0
O B:HOH514 4.7 18.0 1.0
O B:HOH983 4.8 20.8 1.0
O B:HOH661 4.8 13.4 1.0
O B:HOH935 4.8 41.2 1.0
O B:HOH1017 4.8 51.3 1.0
O B:HOH1014 4.9 37.9 1.0

Reference:

E.Hilario, M.F.Dunn, L.J.Mueller, L.Fan. Tryptophan Synthase Q114A Mutant (Internal Aldimine State) in Complex with N-(4'-Trifluoromethoxybenzenesulfonyl) -2-Amino-1-Ethylphosphate (F9F) with Cesium Ion Bound in the Metal Coordination Site. To Be Published.
Page generated: Sat Jul 12 12:15:43 2025

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