Chlorine in PDB 6i9c: Structure of the Otu Domain of Otulin G281R Mutant

All present enzymatic activity of Structure of the Otu Domain of Otulin G281R Mutant:
3.4.19.12;

The structure of Structure of the Otu Domain of Otulin G281R Mutant, PDB code: 6i9c was solved by R.B.Damgaard, P.R.Elliott, K.N.Swatek, E.R.Maher, P.Stepensky, O.Elpeleg, D.Komander, Y.Berkun, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	57.32 / 1.77
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	43.260, 72.437, 93.732, 90.00, 90.00, 90.00
R / Rfree (%)	16.2 / 17.9

The binding sites of Chlorine atom in the Structure of the Otu Domain of Otulin G281R Mutant (pdb code 6i9c). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of the Otu Domain of Otulin G281R Mutant, PDB code: 6i9c:

Chlorine binding site 1 out of 1 in the Structure of the Otu Domain of Otulin G281R Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Otu Domain of Otulin G281R Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl405 b:28.6 occ:1.00 O A:HOH565 3.1 35.5 1.0 NZ A:LYS94 3.3 25.2 1.0 O A:HOH736 3.4 49.1 1.0 CG A:LYS94 3.9 25.1 1.0 CE A:LYS94 4.0 24.9 1.0 O A:HOH637 4.4 38.6 1.0 CD A:LYS94 4.5 25.4 1.0 O A:HOH724 4.8 48.1 1.0 NH2 A:ARG97 5.0 23.9 0.6

R.B.Damgaard, P.R.Elliott, K.N.Swatek, E.R.Maher, P.Stepensky, O.Elpeleg, D.Komander, Y.Berkun. Otulin Deficiency in Oras Causes Cell Type-Specific Lubac Degradation, Dysregulated Tnf Signalling and Cell Death. Embo Mol Med V. 11 2019.
ISSN: ESSN 1757-4684
PubMed: 30804083
DOI: 10.15252/EMMM.201809324