Chlorine in PDB 6jd0: Structure of Mutant Human Cathepsin L, Engineered For Gag Binding

All present enzymatic activity of Structure of Mutant Human Cathepsin L, Engineered For Gag Binding:
3.4.22.15;

The structure of Structure of Mutant Human Cathepsin L, Engineered For Gag Binding, PDB code: 6jd0 was solved by D.Choudhury, S.Biswas, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.41 / 1.81
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	63.835, 64.172, 92.857, 90.00, 90.00, 90.00
R / Rfree (%)	17.1 / 21.5

The structure of Structure of Mutant Human Cathepsin L, Engineered For Gag Binding also contains other interesting chemical elements:

Sodium

(Na)

5 atoms

The binding sites of Chlorine atom in the Structure of Mutant Human Cathepsin L, Engineered For Gag Binding (pdb code 6jd0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of Mutant Human Cathepsin L, Engineered For Gag Binding, PDB code: 6jd0:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Structure of Mutant Human Cathepsin L, Engineered For Gag Binding


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Mutant Human Cathepsin L, Engineered For Gag Binding within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl415 b:46.3 occ:1.00 HO A:POL438 2.6 59.4 1.0 NA A:NA418 2.6 28.9 1.0 H11 A:POL438 2.8 49.3 1.0 H12 A:POL438 2.9 49.3 1.0 C1 A:POL438 3.1 41.1 1.0 O A:POL438 3.2 49.5 1.0 HB3 A:LEU141 3.3 31.1 1.0 HB2 A:LEU141 3.7 31.1 1.0 CB A:LEU141 4.0 25.9 1.0 H A:LEU141 4.0 31.8 1.0 HD23 A:LEU141 4.1 30.6 1.0 HE1 A:PHE135 4.1 28.7 1.0 HD22 A:LEU141 4.3 30.6 1.0 CD2 A:LEU141 4.6 25.5 1.0 C2 A:POL438 4.6 41.9 1.0 N A:LEU141 4.7 26.5 1.0 CE1 A:PHE135 4.9 23.9 1.0 CG A:LEU141 4.9 22.8 1.0 CA A:LEU141 5.0 24.4 1.0

Chlorine binding site 2 out of 3 in the Structure of Mutant Human Cathepsin L, Engineered For Gag Binding


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Mutant Human Cathepsin L, Engineered For Gag Binding within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl416 b:47.1 occ:1.00 HZ3 A:LYS105 2.3 44.6 1.0 NZ A:LYS105 3.2 37.2 1.0 HD3 A:LYS105 3.3 45.2 1.0 HZ2 A:LYS105 3.6 44.6 1.0 HZ1 A:LYS105 3.7 44.6 1.0 CE A:LYS105 4.0 43.9 1.0 HE2 A:LYS105 4.0 52.6 1.0 CD A:LYS105 4.0 37.7 1.0 HD2 A:LYS105 4.5 45.2 1.0 O A:HOH531 4.9 61.6 1.0 HE3 A:LYS105 4.9 52.6 1.0 HB3 A:LYS105 4.9 31.1 1.0

Chlorine binding site 3 out of 3 in the Structure of Mutant Human Cathepsin L, Engineered For Gag Binding


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Mutant Human Cathepsin L, Engineered For Gag Binding within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl417 b:53.2 occ:1.00 H A:LYS213 2.2 31.7 1.0 HA A:PRO212 2.9 27.4 1.0 N A:LYS213 3.1 26.4 1.0 HB3 A:PRO212 3.2 37.0 1.0 HG3 A:LYS213 3.2 35.8 1.0 HB2 A:LYS213 3.4 35.7 1.0 CA A:PRO212 3.6 22.8 1.0 HE21 A:GLN214 3.7 69.9 1.0 CB A:PRO212 3.8 30.9 1.0 C A:PRO212 3.8 27.5 1.0 CB A:LYS213 3.9 29.8 1.0 CG A:LYS213 3.9 29.8 1.0 CA A:LYS213 4.1 25.5 1.0 HD2 A:LYS213 4.1 46.2 1.0 NE2 A:GLN214 4.1 58.2 1.0 HE22 A:GLN214 4.2 69.9 1.0 HE3 A:LYS213 4.3 68.1 1.0 HB2 A:PRO212 4.3 37.0 1.0 CD A:LYS213 4.5 38.5 1.0 HG2 A:LYS213 4.7 35.8 1.0 HG3 A:PRO212 4.7 38.5 1.0 HA A:LYS213 4.8 30.6 1.0 HB3 A:LYS213 4.8 35.7 1.0 C A:LYS213 4.8 26.8 1.0 HG3 A:GLN214 4.9 47.2 1.0 CG A:PRO212 4.9 32.1 1.0 N A:PRO212 4.9 25.6 1.0 CE A:LYS213 4.9 56.7 1.0

D.Choudhury, S.Biswas. Structure of Mutant Human Cathepsin L, Engineered For Gag Binding To Be Published.