Chlorine in PDB 6m12: Crystal Structure of Rnase L in Complex with SU11652

Protein crystallography data

The structure of Crystal Structure of Rnase L in Complex with SU11652, PDB code: 6m12 was solved by J.Tang, H.Huang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 57.30 / 2.40
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 58.710, 110.380, 262.590, 90.00, 90.00, 90.00
R / Rfree (%) 23.1 / 26.6

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Rnase L in Complex with SU11652 (pdb code 6m12). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Rnase L in Complex with SU11652, PDB code: 6m12:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 6m12

Go back to Chlorine Binding Sites List in 6m12
Chlorine binding site 1 out of 2 in the Crystal Structure of Rnase L in Complex with SU11652


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Rnase L in Complex with SU11652 within 5.0Å range:
probe atom residue distance (Å) B Occ
a:Cl801

b:0.1
occ:1.00
CL a:J60801 0.0 0.1 1.0
CAA a:J60801 1.9 95.6 1.0
OD1 a:ASP500 2.4 88.0 1.0
CAB a:J60801 2.8 99.7 1.0
CAD a:J60801 2.9 81.4 1.0
CD1 a:LEU432 3.4 71.3 1.0
N a:ASP500 3.6 55.9 1.0
CG a:ASP500 3.6 81.2 1.0
CD a:LYS390 3.8 73.8 1.0
CB a:ALA499 3.8 51.3 1.0
CA a:ASP500 4.1 64.7 1.0
CAE a:J60801 4.1 86.5 1.0
CAC a:J60801 4.2 85.8 1.0
OE2 a:GLU402 4.3 79.9 1.0
NZ a:LYS390 4.3 74.4 1.0
CB a:ASP500 4.5 75.2 1.0
OD2 a:ASP500 4.5 89.5 1.0
C a:ALA499 4.5 51.2 1.0
CE a:LYS390 4.6 71.5 1.0
CAF a:J60801 4.6 83.7 1.0
CA a:ALA499 4.7 52.9 1.0
CD1 a:ILE377 4.7 70.7 1.0
CB a:LYS390 4.7 64.0 1.0
CG a:LEU432 4.8 65.4 1.0
CG a:LYS390 4.8 67.4 1.0

Chlorine binding site 2 out of 2 in 6m12

Go back to Chlorine Binding Sites List in 6m12
Chlorine binding site 2 out of 2 in the Crystal Structure of Rnase L in Complex with SU11652


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Rnase L in Complex with SU11652 within 5.0Å range:
probe atom residue distance (Å) B Occ
b:Cl802

b:0.9
occ:1.00
CL b:J60802 0.0 0.9 1.0
CAA b:J60802 1.7 87.2 1.0
CAD b:J60802 2.6 78.5 1.0
CAB b:J60802 2.7 76.6 1.0
CD1 b:LEU432 3.3 53.5 1.0
CAE b:J60802 3.8 96.5 1.0
CAC b:J60802 3.9 81.7 1.0
CB b:ALA499 4.1 46.6 1.0
CD1 b:LEU489 4.2 53.7 1.0
OD1 b:ASP500 4.3 93.4 1.0
CAF b:J60802 4.3 91.3 1.0
CD1 b:ILE377 4.5 72.7 1.0
CG b:LEU432 4.6 52.6 1.0
CB b:LEU432 4.7 48.5 1.0
CD b:LYS390 5.0 67.9 1.0

Reference:

J.Tang, Y.Wang, H.Zhou, Y.Ye, M.Talukdar, Z.Fu, Z.Liu, J.Li, D.Neculai, J.Gao, H.Huang. Sunitinib Inhibits Rnase L By Destabilizing Its Active Dimer Conformation. Biochem.J. V. 477 3387 2020.
ISSN: ESSN 1470-8728
PubMed: 32830849
DOI: 10.1042/BCJ20200260
Page generated: Sat Dec 12 13:19:03 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy