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Chlorine in PDB 6nsq: Crystal Structure of Braf Kinase Domain Bound to the Inhibitor 2LEnzymatic activity of Crystal Structure of Braf Kinase Domain Bound to the Inhibitor 2L
All present enzymatic activity of Crystal Structure of Braf Kinase Domain Bound to the Inhibitor 2L:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Braf Kinase Domain Bound to the Inhibitor 2L, PDB code: 6nsq
was solved by
P.Maisonneuve,
I.Kurinov,
A.Assadieskandar,
C.Yu,
C.Zhang,
F.Sicheri,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Braf Kinase Domain Bound to the Inhibitor 2L
(pdb code 6nsq). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Braf Kinase Domain Bound to the Inhibitor 2L, PDB code: 6nsq: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6nsqGo back to Chlorine Binding Sites List in 6nsq
Chlorine binding site 1 out
of 2 in the Crystal Structure of Braf Kinase Domain Bound to the Inhibitor 2L
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6nsqGo back to Chlorine Binding Sites List in 6nsq
Chlorine binding site 2 out
of 2 in the Crystal Structure of Braf Kinase Domain Bound to the Inhibitor 2L
Mono view Stereo pair view
Reference:
A.Assadieskandar,
C.Yu,
P.Maisonneuve,
I.Kurinov,
F.Sicheri,
C.Zhang.
Rigidification Dramatically Improves Inhibitor Selectivity For Raf Kinases. Acs Med.Chem.Lett. V. 10 1074 2019.
Page generated: Sat Dec 12 13:24:47 2020
ISSN: ISSN 1948-5875 PubMed: 31312411 DOI: 10.1021/ACSMEDCHEMLETT.9B00194 |
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